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Casein Kinase 1 Inhibition in Keratinocytes Enhances the Migration of Melanocyte Precursors in the Hair Follicle via KitL/c-Kit Signaling Pathway

research Casein Kinase 1 Inhibition in Keratinocytes Enhances the Migration of Melanocyte Precursors in the Hair Follicle via KitL/c-Kit Signaling Pathway

April 2023 in “Journal of Investigative Dermatology”

Blocking casein kinase 1 in skin cells can help melanocyte precursors move better, potentially helping with conditions like vitiligo or gray hair.

research Rhythmic Expression of Circadian Clock Genes in Human Leukocytes and Beard Hair Follicle Cells

38 citations, August 2012 in “Biochemical and biophysical research communications”

Human leukocytes and beard hair follicle cells have internal daily clocks, and PER1 and PER3 genes may indicate individual circadian rhythms.

research Isolation of Epithelial Stem Cells from Dermis by a Three-Dimensional Culture System

38 citations, January 2006 in “Journal of Cellular Biochemistry”

Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.

Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs

research Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs

11 citations, October 2019 in “Cancers”

Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.

research MiR-92a-1-5p and miR-328-3p Are Up-Regulated in Skin of Female Pattern Hair Loss Patients

4 citations, January 2019 in “Annals of Dermatology”

Higher levels of MiR-92a-1-5p and miR-328-3p found in female hair loss patients.

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Community Join

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community 2 months and half progress. Just take the f*cking pill. (Completely wet hair)

in Progress Pictures 315 upvotes 1 year ago

User shares 2.5-month progress with hair loss pill, others discuss their experiences and results. Some mention using Minoxidil, Finasteride, and microneedling for hair regrowth.

community Breezula hasn't even begun phase 3 trials yet. F*cking hell.

in Treatment 45 upvotes 3 years ago

The conversation is about the delay in Breezula's phase 3 trials and skepticism regarding its effectiveness compared to other treatments like RU58841 and Pyrilutamide. Some users prefer safety over effectiveness, while others express frustration with the slow progress and doubt Breezula will be a significant treatment for hair loss.

community I just made my own PRP - DIY PRP

in Research/Science 549 upvotes 1 year ago

The post and conversation are about a user who made their own Platelet-Rich Plasma (PRP) for hair loss treatment at home, using their own blood and a centrifuge. The responses vary, with some users supporting the DIY approach to save money, others expressing concern about the safety and effectiveness of the method, and a few joking about the lengths people will go to combat hair loss.

community Should i stop the treatment seems like nothing works for me.

in Progress Pictures 23 upvotes 11 months ago

The conversation is about someone considering stopping their hair loss treatment, which includes minoxidil, finasteride, ketoconazole, microneedling, and oral minoxidil, due to lack of visible results. Replies suggest continuing treatment, considering a hair transplant, and trying dutasteride.

community One full year progress on fin + min

in Progress Pictures 517 upvotes 11 months ago

A user shared their one-year progress using finasteride and minoxidil for hair loss, showing significant improvement. They also mentioned using the medication inconsistently and considering changes to their shampoo routine.

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