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GlossaryKeratin 5 (CK5)

protein providing structural support in skin and hair follicles

Keratin 5 (KRT5) is a type of protein found in the skin and hair follicles that helps provide structural support and strength. It is particularly important in the formation of the intermediate filaments in epithelial cells, which are cells that line the surfaces and cavities of the body. Mutations in the KRT5 gene can lead to skin disorders such as epidermolysis bullosa simplex, where the skin becomes fragile and blisters easily.

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research Use of Ultra-Fast One-Step CK5 IHC for Identifying BCC and SCC During Mohs Surgery

1 citations, April 2017 in “Journal of Investigative Dermatology”

A new one-step test can quickly identify skin cancer during surgery.

research Keratinic Amyloid Deposition in Canine Hair Follicle Tumors

1 citations, October 2022 in “Veterinary pathology”

Some canine hair follicle tumors contain amyloid deposits, with a protein called CK5 involved in their formation.

research A Case of Trichogerminoma: A Rare Cutaneous Follicular Neoplasm

December 2021 in “Pathologica”

Trichogerminoma is a rare, benign skin tumor from hair cells, with a small risk of becoming cancerous.

research In Vivo Anti-Trichophyton Activities of Seed Oil Obtained from Caragana Korshinskii Kom.

2 citations, January 2016 in “Skin pharmacology and physiology”

Caragana korshinskii seed oil effectively treats fungal skin infections.

research Dedifferentiation of Committed Epithelial Cells Into Stem Cells In Vivo

551 citations, November 2013 in “Nature”

Certain mature cells in mouse lungs can turn back into stem cells to aid in tissue repair.

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community 8 months of treatment revived my hair

in Progress Pictures 296 upvotes 3 weeks ago

A 24-year-old experienced significant hair regrowth over 8 months using oral finasteride, oral and topical minoxidil, dutasteride, microneedling, and ketoconazole shampoo. They are satisfied with the results and may consider a hair transplant after one year.