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GlossaryKeratin 16 (CK16)

protein providing structural support in skin, hair, and nails

Keratin 16 (K16) is a type of protein found in the skin, hair, and nails that helps provide structural support and resilience. It is particularly important in the body's response to stress or injury, as it is upregulated in conditions like psoriasis and certain types of alopecia, where the skin or hair follicles are damaged.

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research Immunostaining Study of Cytokeratins in Human Hair Follicle Development

2 citations, May 2020 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia”

The study found that specific proteins are markers of hair follicle development in human fetuses.

research 3D-SeboSkin Model Application in Hidradenitis Suppurativa/Acne Inversa

September 2019 in “Journal of Investigative Dermatology”

The 3D-SeboSkin model effectively simulates Hidradenitis suppurativa and is useful for future research.

Androgens Modulate Keratinocyte Differentiation Indirectly Through Enhancing Growth Factor Production From Dermal Fibroblasts

research Androgens Modulate Keratinocyte Differentiation Indirectly Through Enhancing Growth Factor Production From Dermal Fibroblasts

20 citations, January 2019 in “Journal of dermatological science”

Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.

research Cutaneous Adnexal Cysts Revisited: What We Know and What We Think We Know

13 citations, June 2018 in “Dermatopathology”

A new classification system for skin cysts was proposed to improve diagnosis.

Differential Molecular Signature of Dermal Papilla Cells from Balding and Non-Balding Scalp in 2D, 3D Culture and Co-Culture with Adipose-Derived Stem Cells

research Differential Molecular Signature of Dermal Papilla Cells from Balding and Non-Balding Scalp in 2D, 3D Culture and Co-Culture with Adipose-Derived Stem Cells

September 2019 in “Journal of Investigative Dermatology”

Dermal Papilla Cells grown in 3D and with stem cells better mimic natural hair growth conditions than cells grown in 2D.

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