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GlossaryKeratin 16 (CK16)

protein providing structural support in skin, hair, and nails

Keratin 16 (K16) is a type of protein found in the skin, hair, and nails that helps provide structural support and resilience. It is particularly important in the body's response to stress or injury, as it is upregulated in conditions like psoriasis and certain types of alopecia, where the skin or hair follicles are damaged.

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research Solid Basal Cell Epithelioma Possibly Originates From the Outer Root Sheath of the Hair Follicle

61 citations , August 1993 in “PubMed”

Basal cell epithelioma likely starts from the hair follicle's outer root sheath.

research The Changes in the Expression Levels of Follicular Markers in Keratoacanthoma Depend on the Stage: Keratoacanthoma Is a Follicular Neoplasm Exhibiting Infundibular/Isthmic Differentiation Without Expression of CK15

28 citations , February 2014 in “Journal of Cutaneous Pathology”

Keratoacanthoma changes as it grows, showing different hair follicle characteristics at each stage.

research Immunostaining Study of Cytokeratins in Human Hair Follicle Development

2 citations , May 2020 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia”

The study found that specific proteins are markers of hair follicle development in human fetuses.

research 3D-SeboSkin Model Application in Hidradenitis Suppurativa/Acne Inversa

September 2019 in “Journal of Investigative Dermatology”

The 3D-SeboSkin model effectively simulates Hidradenitis suppurativa and is useful for future research.

research An Immunohistochemical Study on Cell Differentiation in the Outer Root Sheath of Normal Human Anagen Hair Follicles with Antikeratin Monoclonal Antibodies

6 citations , December 1990 in “PubMed”

Keratinocytes in hair follicles differentiate similarly to skin cells, with specific patterns in different regions.

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