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GlossaryKeratin 14 (CK14)

protein in skin's basal layer providing structural support

Keratin 14 (KRT14) is a type of protein found in the skin, specifically in the basal layer of the epidermis. It plays a crucial role in providing structural support and resilience to skin cells. Mutations in the KRT14 gene can lead to skin disorders such as epidermolysis bullosa simplex, which causes the skin to be fragile and blister easily.

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research Cytokeratin Expression of Apocrine and Eccrine Poromas with Special Reference to Its Expression in Cuticular Cells

37 citations , August 2000 in “Journal of Cutaneous Pathology”

Poromas are related to sweat duct cells, and CK patterns help distinguish apocrine poromas from other neoplasms.

research Immunostaining Study of Cytokeratins in Human Hair Follicle Development

2 citations , May 2020 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia”

The study found that specific proteins are markers of hair follicle development in human fetuses.

research Are the Meibomian Glands 'Hair Follicles Without a Hair Shaft'?

2 citations , September 2010 in “Acta Ophthalmologica”

Meibomian glands are like hair follicles without a hair shaft.

research Keratinisation Status and Cytokeratins of the Human Meibomian Gland Epithelium

5 citations , September 2009 in “Acta Ophthalmologica”

Hyper-keratinisation in Meibomian glands contributes to gland dysfunction.

research Solid Basal Cell Epithelioma Possibly Originates From the Outer Root Sheath of the Hair Follicle

61 citations , August 1993 in “PubMed”

Basal cell epithelioma likely starts from the hair follicle's outer root sheath.

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