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5 / 148 results

research Body composition and physical fitness in transgender versus cisgender individuals: a systematic review with meta-analysis

February 2026 in “British Journal of Sports Medicine”

Transgender women have similar fitness to cisgender women, while transgender men have higher fat and lower strength than cisgender men; hormone therapy affects body composition and strength.

research Effect of testosterone on chests and abdomens of transgender men

10 citations , January 2019 in “Journal of the American Academy of Dermatology”

This study found that transgender men using testosterone therapy had higher rates of acne and increased body hair growth, resembling male patterns more closely than those not on testosterone.

research The Impact of Gender Affirming Hormone Therapy on Physical Performance

July 2023 in “The Journal of Clinical Endocrinology and Metabolism”

This narrative review suggests that, after at least two years of gender-affirming hormone therapy, nonathletic transgender individuals tend to have physical performance levels similar to cisgender individuals, though more controlled research is necessary, particularly among trans athletes.

research Progesterone in gender-affirming therapy of trans women

11 citations , May 2022 in “World Journal of Biological Chemistry”

This review discusses potential benefits of adding bioidentical progesterone to gender-affirming treatment for trans women and reports no new clinical results; it calls for further research to confirm efficacy and safety.

research SAT645 Cardiac Autonomic Modulation In Transgender Men Under Gender-affirming Hormone Therapy

1 citations , October 2023 in “Journal of the Endocrine Society”

In this study, researchers found that transgender men exhibited impaired autonomic modulation during sympathetic stimulation compared to cisgender women, potentially due to testosterone treatment affecting cardiac autonomic modulation.

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Community Join

5 / 13 results

community (MTF 35) Results of 18 Months of HRT

775 upvotes 8 months ago

A transgender woman experienced significant hair regrowth after 18 months of hormone replacement therapy (HRT) with estrogen and bicalutamide. The discussion notes HRT's effectiveness for hair regrowth but warns against its use for cisgender men due to feminizing effects.

community (MTF 35) 20 Months Feminizing HRT

in Transgender 18 upvotes 7 months ago

A 35-year-old transgender woman experienced hair regrowth with feminizing HRT, adding dutasteride and bicalutamide, and plans a hair transplant for further improvement. Estrogen also improved skin appearance, and the user advises against cisgender men using feminizing HRT for hair regrowth.

community Your Best Advice on MtF Transgender Hair Transplants

4 upvotes 8 years ago

A 37-year-old transgender woman is considering a hair transplant to improve her hairline, as she has minimal hair loss and is on Spironolactone and Estradiol. Users suggest she is a good candidate for the procedure, advising her to research reputable doctors and clinics.

community I don’t understand this, is he equating taking Fin with being on HRT?

303 upvotes 1 year ago

The conversation is about using finasteride and testosterone replacement therapy (TRT) for hair loss and their role in gender-affirming care. It debates whether these treatments are considered hormone replacement therapy (HRT) and their implications for both cisgender and transgender individuals.

community Well… I Did It. Estrogen Saved My Hairline

in Transgender 732 upvotes 2 years ago

OP transitioned and used Spironolactone, Estradiol Valerate, Minoxidil, and dermarolling, resulting in significant hair regrowth. They advise this method may not be suitable for cis men.

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Learn

2 / 801 results

learn Alfatradiol

Does Alfatradiol work the same for women, men, and trans people? Almost all controlled data on topical alfatradiol comes from cisgender women, where it slowed hair loss rather than regrowing hair and was outperformed by minoxidil. No published controlled trial covers cisgender men, and none covers trans people at all — so the honest answer is that the difference has not been measured.

learn Bicalutamide

Could bicalutamide help trans women regrow hair lost to testosterone? No study has tested bicalutamide for hair regrowth in trans women. In cisgender women the only randomized trial found it added nothing to minoxidil, and it is an off-label prescription drug that requires liver monitoring.

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Clinics

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