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research Circulating testosterone and feather-gene expression of receptors and metabolic enzymes in relation to melanin-based colouration in the barn owl

14 citations , September 2017 in “General and comparative endocrinology”

In this study, researchers observed that in barn owls, the relationship between black feather spot size and testosterone levels varied by age and sex, suggesting involvement of genes regulating both traits rather than direct influence of testosterone on feather coloration.

High Circulating Estrone and Low Testosterone Correlate with Adverse Clinical Outcomes in Men with Advanced Liver Disease

research High circulating oestrone and low testosterone correlate with adverse clinical outcomes in men with advanced liver disease

17 citations , March 2016 in “Liver international”

This study found that low serum testosterone and elevated serum oestrone in men with cirrhosis are associated with worse liver disease and adverse health outcomes, suggesting oestrone as a potential ill health marker.

research The circulating dihydrotestosterone/testosterone ratio is increased by gut microbial 5α-reductase activity in females

1 citations , October 2025 in “EBioMedicine”

Women have a higher DHT/testosterone ratio than men, possibly due to gut bacteria activity.

Do 5α-Reductase Inhibitors Raise Circulating Serum Testosterone Levels? A Comprehensive Review and Meta-Analysis Explaining Paradoxical Results

research Do 5α-Reductase Inhibitors Raise Circulating Serum Testosterone Levels? A Comprehensive Review and Meta-Analysis to Explaining Paradoxical Results

5 citations , August 2018 in “Sexual Medicine Reviews”

In this review and meta-analysis, the authors concluded that 5α-reductase inhibitor therapy is not consistently associated with significant increases in serum testosterone levels in men.

Behavior of the Two Circulating Androgens Testosterone and DHEA and Their Main Intracellular Metabolites in an Androgen-Sensitive Sebocyte Cell Line

research 892 Behavior of the two circulating androgens testosterone and DHEA and their main intracellular metabolites in an androgen-sensitive sebocyte cell line

April 2019 in “Journal of Investigative Dermatology”

In this study, engineered mice with a mutation similar to that in Olmsted syndrome showed progressive hair loss due to impaired inner root sheath keratinocyte differentiation and stem cell exhaustion.

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community My Testosterone is less than 1/3rd In 7 Months since I took Finasteride!

114 upvotes 3 years ago

A user experienced a significant drop in testosterone levels after taking finasteride, leading to side effects like low libido and muscle mass loss. Despite its effectiveness for hair, the user decided to stop finasteride due to its impact on hormones, preferring to be bald.

community DHT/Testosterone levels in scalp Fin VS Dut.

in Finasteride/Dutasteride 66 upvotes 2 years ago

Dutasteride raises scalp testosterone by 99%, which may not be ideal for those sensitive to all androgens. Some argue finasteride's balancing act might be better, while others believe dutasteride is superior for hair regrowth.

community My Testosterone results before and after Finasteride

147 upvotes 5 years ago

Finasteride significantly increased testosterone levels for the user, with no major side effects except watery semen, which was resolved with zinc supplements. The user's hairline stopped receding and slightly improved.

community Finasteride doubled my testosterone & estrogen

in Chat 265 upvotes 10 months ago

Finasteride increased testosterone and estrogen, stopped hair loss, and promoted regrowth. Users discussed side effects like libido changes and considered adding minoxidil and aromatase inhibitors.

community Testosterone and Estradiol levels on 1 mg/day dutasteride

43 upvotes 11 months ago

A 30-year-old man experienced significant hair regrowth and improved libido after using finasteride and dutasteride for androgenetic alopecia, with no adverse effects. He plans to reduce dutasteride dosage when trying to conceive and has been using topical minoxidil since 2015.

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Learn

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learn Dutasteride

Heavy duty finasteride that comes with higher risks

learn Rosemary

herb and oil with stimulant, circulatory, anti-inflammatory and antioxidant properties

Rosemary helps circulation, but does that actually regenerate hair? Rosemary may improve circulation but does not directly regenerate hair.

learn Stem Cell Factor

learn vitamin b2

How does Vitamin B2 support scalp circulation and cellular energy production? Vitamin B2 enhances scalp circulation and energy production by supporting cellular metabolism.

learn capsicum

How does capsicum improve scalp circulation and boost growth? Capsaicin dilates blood vessels through TRPV1 activation, so capsicum is expected to raise scalp blood flow, but every human hair-loss study used it inside a multi-ingredient formula — and the strongest one gave it orally, not on the scalp — so its effect on hair by itself is unproven, and it is a known skin irritant.

learn Ginkgo biloba

How does ginkgo biloba improve scalp circulation and does that help with hair regrowth? Ginkgo biloba may improve scalp circulation, but evidence for hair regrowth is inconclusive.

learn Vitis vinifera

Can grape extract help with scalp circulation or hair growth? Grape extract may improve scalp circulation but lacks strong evidence for hair growth.

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