research Vitamin D, Lipid Metabolism and Prostate Cancer
This study found that vitamin D regulates cholesterol metabolism and may influence prostate cancer development through mechanisms affecting prostate cell growth and sex hormone metabolism.
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5 / 1000+ resultsresearch 25 Hydroxyvitamin D 1 α-Hydroxylase Is Required for Optimal Epidermal Differentiation and Permeability Barrier Homeostasis
This study found that mice lacking the 1αOHase enzyme, which is responsible for producing a key vitamin D metabolite, showed impaired epidermal differentiation and delayed recovery of skin barrier function after disruption.
research Normal Fur Development and Sebum Production Depends on Fatty Acid 2-Hydroxylase Expression in Sebaceous Glands
This study revealed that deficiency in the enzyme FA2H in mice affected sebaceous gland function, altered sebum composition, and caused cycling alopecia, highlighting FA2H's role in hair follicle homeostasis.
research Altered Hormone and Bioactive Lipid Plasma Profile in Rodent Models of Polycystic Ovarian Syndrome Revealed by Targeted Mass Spectrometry
This study found that while rat models treated with letrozole and dihydrotestosterone exhibit altered sterol, leukotriene, and steroid hormone profiles similar to human PCOS, significant differences remain.
research Cholesterol promotes hair growth through activating sympathetic nerves and enhancing the proliferation of hair follicle stem cells
This study on C57BL/6 mice found that subcutaneous cholesterol injections significantly promoted hair regeneration by enhancing hair follicle stem cell proliferation, highlighting the role of the PKA-tyrosine hydroxylase-sympathetic nervous system pathway in this process.
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5 / 1000+ resultscommunity Been on Fin 1 year and 7 months and 2.5 Oral minoxidil for 6 months
The user has been using finasteride for 1 year and 7 months and oral minoxidil for 6 months, noticing peach fuzz that may turn into terminal hair. The user has experienced no side effects and is considering additional treatments like dermarolling and possibly increasing the minoxidil dose.
community 3.5 months minoxidil , 2.5 months 1mg fin update ( also 22 kg weight loss in 6 months! )
A 21-year-old experienced hair regrowth and improved health after using topical minoxidil, finasteride, and zinc shampoo, alongside lifestyle changes like weight loss and exercise. They also started microneedling and managed seborrheic dermatitis with benzoyl peroxide mixed in shampoo.
community Convinced dad to get into minox 3 months ago and fin 2 months ago
A user convinced their 45-year-old dad to use minoxidil and finasteride, resulting in significant hair regrowth. The dad now uses 1mg of finasteride daily and topical minoxidil twice a day, and has also started using 1% ketoconazole shampoo.
community Bad doctors even in the USA
Young men are advised to delay hair transplants until after age 25, using finasteride, minoxidil, and dermarolling to manage hair loss. Concerns about unethical doctors highlight the need for careful planning.
community Still receding on dutasteride after 18 months
A 21-year-old male has been using dutasteride for 18 months and a topical minoxidil/finasteride solution for 2.5 years, but his hairline continues to recede. He is considering switching back to finasteride, as some users suggest increasing the dutasteride dose or adding other treatments like ketoconazole shampoo.
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