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research Hair Growth Defects in Insig-Deficient Mice Caused by Cholesterol Precursor Accumulation and Reversed by Simvastatin

46 citations, January 2010 in “The journal of investigative dermatology/Journal of investigative dermatology”

Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.

Sterol Intermediates of Cholesterol Biosynthesis Inhibit Hair Growth and Trigger an Innate Immune Response in Cicatricial Alopecia

research Sterol Intermediates of Cholesterol Biosynthesis Inhibit Hair Growth and Trigger an Innate Immune Response in Cicatricial Alopecia

22 citations, June 2012 in “PLOS ONE”

Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.

research Cholesterol Homeostasis: Links to Hair Follicle Biology and Hair Disorders

25 citations, July 2019 in “Experimental Dermatology”

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

research Disrupted Cholesterol Biosynthesis and Hair Follicle Stem Cell Impairment in the Onset of Alopecia

November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.

Both Low Circulating Insulin-Like Growth Factor-1 and High-Density Lipoprotein Cholesterol Are Associated with Hair Loss in Middle-Aged Women

research Both Low Circulating Insulin-Like Growth Factor-1 and High-Density Lipoprotein Cholesterol Are Associated with Hair Loss in Middle-Aged Women

6 citations, March 2016 in “British Journal of Dermatology”

Low IGF-1 and high HDL cholesterol levels are linked to more hair loss in middle-aged women.

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community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

in Research/Science 479 upvotes 4 months ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Is it me or are people losing their hair very young now?

in Finasteride/Dutasteride 143 upvotes 4 years ago

People notice more young individuals experiencing hair loss and discuss possible reasons, such as diet, hormones, and stress. Some treatments mentioned include finasteride, dutasteride, and minoxidil.

community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

in Update 35 upvotes 5 years ago

The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

community Dutasteride broked my liver (maybe)

in Finasteride/Dutasteride 8 upvotes 2 years ago

A user shared their experience with high cholesterol, glucose, and potential metabolic syndrome after using Finasteride and Dutasteride for hair loss. They plan to improve their health with diet and exercise before considering medication.

community Proof that finasteride messes with neurosteroids

in Research/Science 230 upvotes 5 months ago

Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

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