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Localization and Regulation of Cholesterol Transporters in the Human Hair Follicle: Mapping Changes Across the Hair Cycle

research Localisation and regulation of cholesterol transporters in the human hair follicle: mapping changes across the hair cycle

13 citations , January 2021 in “Histochemistry and Cell Biology”

In this study, human hair follicles showed varying expression of cholesterol transport proteins during the hair cycle, suggesting a potential role of cholesterol in hair growth and cycling.

research Lifestyle changes in women with polycystic ovary syndrome

198 citations , July 2011 in “Cochrane library”

This study found that lifestyle interventions improved body composition, hyperandrogenism, and insulin resistance in women with PCOS, but did not affect glucose tolerance, lipid profiles, or clinical reproductive outcomes.

Physical Changes, Laboratory Parameters, and Bone Mineral Density During Testosterone Treatment in Adolescents with Gender Dysphoria

research Physical Changes, Laboratory Parameters, and Bone Mineral Density During Testosterone Treatment in Adolescents with Gender Dysphoria

71 citations , August 2019 in “The journal of sexual medicine”

In this study, transgender adolescents treated with testosterone for a median of 12 months experienced effective virilization, including voice deepening and increased hair growth, but also showed decreased HDL cholesterol and BMD z-scores, and increased hematocrit, with no short-term safety issues reported.

research Changes of metabolic profile in men treated for androgenetic alopecia with 1 mg finasteride

24 citations , January 2010 in “Endocrine Regulations”

In this study, men taking 1 mg/day of finasteride for 12 months showed minor metabolic changes and slight improvements in glucose metabolism.

research Inactivation of autophagy leads to changes in sebaceous gland morphology and function

27 citations , July 2018 in “Experimental dermatology”

This study found that autophagy plays a role in sebaceous gland function and sebum composition control in mice lacking the Atg7 gene in keratinocytes.

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community Dutasteride and elevated (LDL) cholesterol

1 upvotes 1 year ago

The user switched from finasteride to dutasteride for hair loss and noticed elevated cholesterol levels, questioning if dutasteride caused this change. They also take Vitamin D, biotin, magnesium, ginkgo biloba, omega-3, and NAC, and are concerned about the impact of these supplements and their health on cholesterol levels.

community Finasteride, also known as Propecia or Proscar, treats male pattern baldness and enlarged prostate in millions of men worldwide. But a new study suggests the drug may also provide a surprising and life-saving benefit: lowering cholesterol and cutting the overall risk of cardiovascular disease.

in Research/Science 531 upvotes 2 years ago

The conversation discusses the potential benefits of finasteride (Fin) for lowering cholesterol and reducing cardiovascular disease risk, with users sharing personal experiences and opinions on the medication's effects on health and hair loss. Some users report positive changes in cholesterol levels after taking finasteride, while others are skeptical or joke about its effects.

community Fin ED is primarily blood flow related, not hormonal as such - a theory

7 upvotes 5 years ago

The conversation discusses the theory that finasteride-induced erectile dysfunction (ED) is related to blood flow rather than hormonal changes. The user suggests that lowering LDL cholesterol aggressively might improve ED symptoms for those on finasteride.

community 5ARI (dutasteride) Associated with Adverse Metabolic Effects

24 upvotes 8 years ago

Dutasteride is associated with increased blood glucose, HbA1c, LDL cholesterol, and liver enzyme activity, potentially leading to diabetes, NAFLD, and liver metabolism changes. The conversation highlights concerns about these adverse effects and calls for more studies, including on finasteride.

community What happens to the excess testosterone after using dut?

in Finasteride/Dutasteride 23 upvotes 1 year ago

Using dutasteride or finasteride can increase free testosterone, which may convert to estradiol, potentially causing side effects like increased estrogen levels. Individual responses vary, and some users report changes in cholesterol, hair texture, and side effects like gyno or increased sex drive.

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