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GlossaryChlorambucil

chemotherapy drug that treats certain cancers by disrupting DNA replication

Chlorambucil is a chemotherapy drug used to treat certain types of cancer, such as chronic lymphocytic leukemia and some types of lymphoma. It works by interfering with the DNA replication process in cancer cells, thereby preventing their growth and multiplication.

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research Scraggly: A New Hair Loss Mutation on Mouse Chromosome 19

14 citations , September 1999 in “Mammalian genome”

The scraggly mutation causes hair loss and skin defects in mice.

research Chemotherapy in Gynecologic Malignancy

March 1965 in “Hospital Topics”

Chemotherapy provides symptom relief and extends life in 30-50% of gynecological cancer cases, but has only cured choriocarcinoma.

research Feline Pemphigus Foliaceus: A Retrospective Analysis of 57 Cases

64 citations , December 2003 in “Veterinary Dermatology”

Triamcinolone is more effective and safer for treating feline pemphigus foliaceus than prednisone.

research Follicular Mucinosis in Association with Sézary Syndrome

17 citations , May 1987 in “Clinical and Experimental Dermatology”

A patient with Sézary syndrome showed improvement after treatment and the study suggested follicular mucinosis might indicate future lymphoma risk.

research Bendamustine: An Old Drug in the New Era for Patients with Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia

9 citations , January 2018 in “Acta Clinica Croatica”

Bendamustine, often combined with other drugs, is effective and less toxic for certain blood cancers, but less effective for young, fit patients with CLL.

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