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GlossaryCytotoxic Drugs (Chemotherapeutic Agents)

medications that kill or inhibit rapidly dividing cells

Cytotoxic drugs, also known as chemotherapeutic agents, are medications designed to kill or inhibit the growth of rapidly dividing cells, such as cancer cells. While effective in treating various cancers, these drugs can also affect healthy cells that divide quickly, like those in hair follicles, leading to side effects such as hair loss (alopecia).

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research Adverse Cutaneous Reactions to Chemotherapeutic Agents and Cytokine Therapy

18 citations, December 1996 in “Seminars in Cutaneous Medicine and Surgery”

Chemotherapy and cytokine therapy can cause various skin reactions, including hair loss and hypersensitivity.

research Cutaneous Complications of Chemotherapeutic Agents

172 citations, November 1983 in “Journal of The American Academy of Dermatology”

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

research Cutaneous Reactions to Chemotherapeutic Agents

53 citations, May 2001 in “The American journal of the medical sciences”

Chemotherapy can cause various skin problems, and recognizing them helps improve patient care.

research Dermatological Adverse Effects of Chemotherapeutic Agents: Experience from a Tertiary Centre

June 2017 in “Journal of evolution of medical and dental sciences”

About 22% of cancer patients had skin-related side effects from chemotherapy, but these were usually not severe enough to halt treatment.

research Conceptual Basis for Use of Chemotherapeutic Agents and Their Pharmacology

3 citations, February 1976 in “Pediatric Clinics of North America”

The conclusion is that effective cancer treatment often requires a combination of therapies, but must be carefully managed due to serious side effects and the risk of immunosuppression.

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