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research Testosterone Enhances Expression and Functional Activity of Epithelial Sodium Channel, Cystic Fibrosis Transmembrane Regulator, and Sodium Hydrogen Exchanger in Vas Deferens of Sex-Steroid Deficient Male Rats

6 citations, July 2018 in “Steroids”

Testosterone changes how certain channels work in male rat reproductive tracts, affecting fertility-related fluid balance.

research CFTR Potentiator Ivacaftor Protects Against Noise-Induced Hair Cell Loss by Increasing Nrf2 and Reducing Oxidative Stress

4 citations, August 2023 in “Biomedicine & Pharmacotherapy”

Ivacaftor can protect against noise-induced hearing loss by reducing oxidative stress.

research Androgen Profile Through Life in Women With Polycystic Ovary Syndrome: A Nordic Multicenter Collaboration Study

71 citations, July 2015 in “The Journal of Clinical Endocrinology and Metabolism”

Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.

research Effects of Lifelong Testosterone Exposure on Health and Disease Using Mendelian Randomization

29 citations, October 2020 in “eLife”

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

research Testosterone, Dihydrotestosterone, and Incident Cardiovascular Disease and Mortality in the Cardiovascular Health Study

104 citations, March 2014 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

DHT may increase the risk of heart disease and death in elderly men.

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Community Join

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community Dutasteride 3 and a half month update

in Finasteride/Dutasteride 51 upvotes 1 year ago

The user's experience with hair loss treatments such as finasteride, dutasteride, and minoxidil, and how they are affecting their density. Replies to the post suggest different hairstyles and hair transplant options, and provide encouragement for the original poster's situation.

community Do I get a hair transplant at 22?

in Transplants 11 upvotes 6 months ago

A user has been using dutasteride and oral minoxidil for hair loss with no change and is considering a hair transplant at age 22. Replies suggest that a transplant is possible if DHT blockers like finasteride are continued, and another user shared a positive personal experience with a transplant at age 20.