research Case Report: Heterozygous Mutation in HTRA1 Causing Typical Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
A heterozygous mutation in HTRA1 can cause severe CARASIL symptoms.
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5 / 1000+ resultsresearch HtrA1L364P Leads to Cognitive Dysfunction and Vascular Destruction Through TGF-β/Smad Signaling Pathway in CARASIL Model Mice
The HtrA1L364P mutation causes brain dysfunction and blood vessel damage.
research A Frameshift Mutation in HTRA1 Expands CARASIL Syndrome and Peripheral Small Arterial Disease to the Chinese Population
A new genetic mutation linked to CARASIL syndrome and small artery disease was found in a Chinese family.
research RBPJ Mutations Identified in Two Families Affected by Adams-Oliver Syndrome
Mutations in the RBPJ gene cause Adams-Oliver Syndrome.
research Inhibition of JAK-STAT Signaling with Baricitinib Reduces Inflammation and Improves Cellular Homeostasis in Progeria Cells
Baricitinib reduces inflammation and improves cell health in premature aging cells.
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5 / 15 resultscommunity 1 year on Finasteride - I think it worked.
The user shared progress pictures after one year on finasteride, suggesting it was effective for hair loss. The conversation includes humorous and sarcastic comments about the results and side effects.
community 60 days on topical minoxidil 5% + 0.1% finasteride.
The user is happy with hair regrowth after 60 days using topical minoxidil 5% and finasteride 0.1%, along with a dermaroller. They report no significant side effects and plan to continue treatment for a year.
community Just over 4 months in. Am I seeing things?
The user reports potential hair regrowth after using finasteride nightly, minoxidil twice daily, occasional microneedling, and vitamin supplements, and is considering RU58841 in the future. Replies suggest they are seeing improvement.
community Methionine? Glycine?
The conversation discusses the potential benefits and risks of using Methionine and Glycine for hair loss, with concerns about cancer risk if not balanced properly. The user seeks opinions on these amino acids for hair health and overall benefits.
community EU Shouldn't Ban Fin & Dut: PFS is NOT REAL.
Finasteride and Dutasteride do not cause depression or "Post Finasteride Syndrome," with concerns often linked to the nocebo effect and preexisting mental health issues. The EU is unlikely to ban these drugs, but access may become more restricted due to ongoing debates.