In this study, researchers found that changes in immune cell infiltration and immune-related gene expression may contribute to the immune microenvironment changes in male androgenetic alopecia.
November 2023 in “Journal of Investigative Dermatology”
This research investigated immune cell involvement in various types of inflammatory alopecia by analyzing gene expression data from scalp samples, revealing distinct cellular changes in conditions like Alopecia Areata, Frontal Fibrosing Alopecia, Lichen Planopilaris, and Central Centrifugal Cicatricial Alopecia, which may inform future therapeutic targets.
155 citations
,
May 2016 in “Nature communications”
This study found that mouse skin CD4(+) memoryTcells are in equilibrium with the circulation under steady state but increase in specific clusters in response to infection or inflammation.