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Glossary Centella asiatica

medicinal herb used for wound healing and hair health

Centella asiatica, also known as Gotu Kola, is a medicinal herb commonly used in traditional medicine for its potential health benefits. It is known for its ability to promote wound healing, improve circulation, and enhance cognitive function. In the context of hair care, Centella asiatica is often included in formulations to strengthen hair, reduce hair loss, and improve scalp health due to its anti-inflammatory and antioxidant properties.

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Research

5 / 303 results

research Centella asiatica L. Urb. Extracellular Vesicle and Growth Factor Essence for Hair and Scalp Health: A 56-Day Exploratory Randomized Trial

November 2025 in “Cosmetics”

In this exploratory randomized controlled trial, participants using a combination of Centella asiatica-derived extracellular vesicles with recombinant growth factors showed significant improvements in hair thickness, density, length, and reduced hair loss and scalp sebum content after 56 days, compared to placebo.

research Targeting the hallmarks of aging: preclinical evidence and molecular mechanisms underlying the therapeutic potential of Centella asiatica (L.) Urban

June 2026 in “Journal of Biological Studies”

This review synthesizes preclinical evidence suggesting that Centella asiatica may extend healthspan by modulating aging hallmarks, enhancing DNA repair, improving mitochondrial function, and reducing inflammation and oxidative stress, potentially paving the way for future gerotherapeutic strategies.

research Oral Centella asiatica Extract Attenuates UVB-Induced Skin Photoaging via Antioxidant, Anti-Inflammatory, and Extracellular Matrix-Preserving Effects in Hairless Mice

December 2025 in “International Journal of Molecular Sciences”

In this study, orally administered Centella asiatica extract, standardized for asiaticoside content, significantly improved skin barrier function, elasticity, and reduced signs of UVB-induced photoaging in hairless mice, highlighting its potential as a nutricosmetic for skin health.

A 56-Day Randomized, Double-Blinded, and Placebo-Controlled Clinical Assessment of Scalp Health and Hair Growth Parameters with a Centella Asiatica Extracellular Vesicle and Growth Factor-Based Essence

research A 56-Day Randomized, Double-Blinded, and Placebo-Controlled Clinical Assessment of Scalp Health and Hair Growth Parameters with a Centella asiatica Extracellular Vesicle and Growth Factor-Based Essence

September 2025 in “medRxiv (Cold Spring Harbor Laboratory)”

This study found that applying a topical scalp essence with Centella asiatica extracellular vesicles and growth factors significantly improved scalp health and hair growth compared to a placebo after 56 days.

research Enhanced VEGF Expression in Hair Follicle Dermal Papilla Cells by Centella asiatica Linn.

3 citations , January 2018 in “Chiang Mai University Journal”

This study found that while the EtOAc fraction of Centella asiatica had the highest antioxidant activity, it was toxic to human follicle dermal papilla cells, but the EtOH crude extract promoted hair growth by enhancing VEGF expression.

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Community Join

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community Scientists have uncovered a simple way to cure hair loss – as incredible before–and–after photos show the results in just 8 weeks

in Research/Science 283 upvotes 11 months ago

Scientists claim a combination of caffeine, two proteins, and Centella asiatica extracts can cure hair loss, but skepticism remains due to past unfulfilled promises. Users discuss various treatments like minoxidil, finasteride, and microneedling, expressing doubt about the effectiveness of new methods.

community Serum based on plant extracts boosts hair growth in weeks.

44 upvotes 11 months ago

A serum containing Centella asiatica extracellular vesicles, IGF-1, FGF-7, and caffeine significantly improved hair thickness, density, length, and reduced hair loss after 56 days. The conversation also discusses how treatments like finasteride, minoxidil, and ketoconazole address different aspects of hair loss by reducing DHT, improving blood flow, and lowering inflammation.

community Exosomes 2 months before and after

7 upvotes 1 year ago

Exosomes are being discussed as a potential hair loss treatment, with some users skeptical about their effectiveness and stability. There is interest in different types of exosomes, including those derived from centella asiatica, and comparisons are made to other treatments like finasteride.

community New plant-based serum shown to regrow hair in weeks, according to scientists

in Treatment 274 upvotes 8 months ago

A new plant-based serum is claimed to regrow hair in weeks, but users are skeptical about its effectiveness and the reliability of the study. Ingredients like Centella Asiatica and IGF-1 are mentioned, but many doubt the serum's superiority over existing treatments like Minoxidil and finasteride.

community Best science-backed supplements for androgenetic alopecia? Looking for real evidence

7 months ago

The conversation discusses treatments for androgenetic alopecia, focusing on evidence-based supplements to complement finasteride. Suggestions include oral minoxidil, saw palmetto, pumpkin seed oil, tocotrienols, and various other supplements, while emphasizing the importance of scientific backing and cautioning against saw palmetto if already using finasteride.

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Learn

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learn Centella

Not eating well lately and your hair’s falling? A centella-based supplement might give your roots the boost they’re begging for. There is no published human trial showing that an oral Centella asiatica (gotu kola) supplement stops hair shedding caused by poor nutrition; the evidence is laboratory work on dermal papilla cells, inflammation and collagen, and community reports mention centella only in topical products.
Sensitive to hormones? A centella scalp mask may help ease hidden inflamm Centella asiatica has anti-inflammatory and wound-healing effects in animal and cell studies, but no published research has tested a centella scalp mask on the human scalp, in hormonal contexts or otherwise, and no community reports were found of one being used this way.
Ever wonder why your hair doesn’t grow back thick anymore? Maybe your scalp needs better blood flow: centella could help. There is no clinical trial of centella asiatica for hair loss and no study measuring scalp blood flow in people using it; the only hair-related evidence is a 2017 cell-culture study. Centella products are cosmetics that may soothe an irritated scalp, and the link between scalp circulation and pattern hair loss is itself unproven.
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