92 citations
,
April 2009 in “Journal of Investigative Dermatology” The Celsr1 gene is crucial for normal hair patterning in mice.
7 citations
,
January 2023 in “Frontiers in cell and developmental biology” This study found that Celsr1, not Celsr2, is the primary protein involved in establishing planar cell polarity and hair follicle polarization in the epidermis of mice.
November 2024 in “Journal of Investigative Dermatology” Genetic defects in the Wnt/PCP pathway may cause congenital yellow nail syndrome.
55 citations
,
November 2010 in “Development” This study observed that in frizzled 6 null mice, initially uncorrelated hair follicle orientations develop into highly ordered patterns over time, suggesting possible mechanisms for biological structure patterning.
33 citations
,
August 2000 in “Experimental Cell Research”