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      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

      learn Ketoconazole

      antifungal with some anti-androgenic benefits, often used as a shampoo

      learn Platelet-Rich Plasma

      growth factors taken from your blood and injected into your scalp to stimulate hair

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      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

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      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 4 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Wtf have we been doing for the last 30 years

      in Treatment  548 upvotes 1 month ago
      Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.