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This study investigated improving Finasteride's water solubility using trimethyl-β-cyclodextrin (TM-β-CD) and β-cyclodextrin (β-CD) as carriers, finding that β-CD improved Fin's cumulative release, while TM-β-CD enhanced its solubility, with computational data supporting these outcomes.

The researchers found that corneodesmosin is crucial for maintaining skin barrier integrity and hair follicle architecture in mice, with its deletion leading to severe skin and hair abnormalities.

This review identifies genetic mutations associated with congenital hair loss disorders in Japanese populations, particularly highlighting common LIPH gene mutations linked to woolly hair/hypotrichosis, and reports no new clinical results.

This overview discusses advancements in the understanding of molecular genetics in heritable keratinization disorders, focusing on recent cases of inherited ichthyosis, and reports no new clinical results.

Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.