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    Glossary CDK inhibitors

    block enzymes that regulate cell cycle progression

    CDK inhibitors, or Cyclin-dependent kinase inhibitors, are a class of drugs that block the activity of enzymes known as cyclin-dependent kinases (CDKs). These enzymes play a crucial role in regulating the cell cycle, and their inhibition can halt the proliferation of cancer cells, making CDK inhibitors valuable in cancer treatment.

    Research 10 of 432

    1. Alopecia induced by CDK 4/6 Inhibitors and its Impact on the Quality of Life of Patients with advanced Breast cancer 2025
    2. Retrospective cohort study of CDK4/6-inhibitor-induced alopecia in breast cancer patients Supportive Care in Cancer · 2023 · 9 citations
    3. CDK4/6 plus aromatase inhibitor-induced alopecia in breast cancer patients. Journal of Clinical Oncology · 2019 · 4 citations
    4. Hormone receptor positive, HER2 negative metastatic breast cancer: Impact of CDK4/6 inhibitors on the current treatment paradigm Asia-Pacific Journal of Clinical Oncology · 2018 · 4 citations
    5. Impact of CDK4/6 inhibitors on health-related quality of life outcomes in patients with metastatic breast cancer: A systematic review and meta-analysis Journal of Managed Care & Specialty Pharmacy · 2025 · 1 citations
    6. Safety and quality of life of CDK4/6 inhibitors therapy for hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer: a multicenter cross-sectional survey in China BMC Cancer · 2025 · 1 citations
    7. Safety and patient-reported outcomes in patients with hormone receptor-positive, HER2-negative advanced breast cancer treated with CDK4/6 inhibitors in China: A cross-sectional study. Journal of Clinical Oncology · 2024
    8. Retrospective cohort study of CDK4/6-inhibitor-induced alopecia in patients with breast cancer. Journal of Clinical Oncology · 2023
    9. Patient, Oncologist, and Payer Preferences for Adjuvant Endocrine Therapy and CDK4/6 Inhibitor Regimens in Early-Stage Breast Cancer: A Discrete Choice Experiment Patient Preference and Adherence · 2021 · 12 citations
    10. CDK4/6 inhibition mitigates stem cell damage in a novel model for taxane‐induced alopecia EMBO Molecular Medicine · 2019 · 58 citations
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