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GlossaryP-cadherin (CDH3)

protein aiding cell adhesion in tissue structure maintenance

P-cadherin is a protein that helps cells stick together, playing a crucial role in maintaining the structure of tissues, including hair follicles. It is part of the cadherin family, which are important for cell adhesion, signaling, and maintaining the integrity of tissues. In the context of hair, abnormalities in P-cadherin expression can be linked to hair loss conditions like alopecia.

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research Homozygous Deletion in CDH3 and Hypotrichosis With Juvenile Macular Dystrophy

15 citations , November 2012 in “Archives of Ophthalmology”

A deletion in the CDH3 gene causes a rare disorder with short hair and vision loss.

research A Novel Nonsense CDH3 Mutation in Hypotrichosis with Juvenile Macular Dystrophy

13 citations , February 2012 in “International Journal of Dermatology”

A new genetic mutation in the CDH3 gene causes hair loss and eye problems in young people.

research CDH3 Gene Related Hypotrichosis and Juvenile Macular Dystrophy: A Case with a Novel Mutation

9 citations , June 2017 in “American journal of ophthalmology. Case reports”

A new mutation in the CDH3 gene causes hair loss and vision problems in a young girl.

research Phenotypic Diversity and Mutation Spectrum in Hypotrichosis with Juvenile Macular Dystrophy

52 citations , November 2003 in “Journal of Investigative Dermatology”

Different harmful mutations in the CDH3 gene cause HJMD, but symptoms vary among individuals.

research Hypotrichosis With Juvenile Macular Dystrophy: A Case Report With Molecular Study

5 citations , January 2017 in “Arquivos Brasileiros de Oftalmologia”

A rare genetic disorder causes sparse hair and vision loss due to a CDH3 gene mutation.

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