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GlossaryCD4+ T cells (T-helper cells)

specialized white blood cells that coordinate immune responses

CD4+ T cells, also known as T helper cells, are a type of white blood cell that plays a crucial role in the immune system. They help coordinate the body's response to infections by signaling other immune cells, such as B cells and cytotoxic T cells, to perform their functions. These cells are essential for mounting an effective immune response and are notably targeted by HIV, which can lead to a weakened immune system.

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research Hepatitis C-Related Mixed Type Vitiligo in a Patient with Ivemark Syndrome

1 citations, January 2014 in “The Journal of Dermatology”

A patient with Ivemark syndrome developed mixed type vitiligo after a hepatitis C infection, showing different treatment responses and immune cell involvement in the skin.

research PD-1+ CXCR5− CD4+ T Cells Are Correlated with the Severity of Systemic Lupus Erythematosus

71 citations, May 2019 in “Rheumatology”

Tph cells are linked to the severity of systemic lupus erythematosus.

research Identification of Distinct Immune Signatures and Chemokine Networks in Scalp Inflammatory Diseases

June 2023 in “Research Square (Research Square)”

Different immune responses cause hair loss in scalp diseases, with unique patterns in scalp psoriasis possibly protecting against hair loss.

research Disturbance of Immune Microenvironment in Androgenetic Alopecia Through Spatial Transcriptomics

August 2024 in “International Journal of Molecular Sciences”

Androgenetic alopecia involves immune cell disruptions, especially increased CD4+ T cells around hair follicles.

Ex Vivo Treatment with Allogenic Mesenchymal Stem Cells on Peripheral Blood Mononuclear Cells of Patients with Severe Alopecia Areata

research Ex Vivo Treatment with Allogenic Mesenchymal Stem Cells on Peripheral Blood Mononuclear Cells of Patients with Severe Alopecia Areata

1 citations, October 2022 in “International Journal of Molecular Sciences”

Using healthy donor stem cells can potentially calm overactive immune cells and reduce inflammation in severe hair loss patients, offering a possible treatment method.

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