39 citations
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May 2014 in “Frontiers in Pharmacology”
In this study, CD4+CD25+FoxP3+ RegulatoryTcells were found to reduce TGF-b1 induced lung fibrosis and fibrocyte accumulation in mice, partly by suppressing fibroblast growth factor 9.
This study found that T-regulatorycells, specifically the FOXP3 CD39 subset, were significantly reduced in both circulation and hair follicles of alopecia areata patients compared to healthy subjects, suggesting potential therapeutic targets.
21 citations
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April 2019 in “Journal of cutaneous pathology”
This study found a significant reduction in Treg cell frequency in alopecia areata compared to other autoimmune and non-autoimmune skin diseases using immunohistochemical staining.