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GlossaryDipeptidyl Peptidase-4 (CD26)

enzyme that breaks down incretin hormones, regulating insulin levels

Dipeptidyl Peptidase-4 (DPP-4) is an enzyme that plays a role in glucose metabolism by breaking down incretin hormones, which help regulate insulin levels in the body. It is also known as CD26 and is involved in immune system functions. Inhibitors of DPP-4 are used in the treatment of type 2 diabetes to improve blood sugar control.

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research The Influence of CD26+ and CD26− Fibroblasts on the Regeneration of Human Dermo-Epidermal Skin Substitutes

11 citations , February 2022 in “Scientific Reports”

CD26+ fibroblasts improve skin healing and integration better than CD26− fibroblasts.

research Fibroblasts – The Cellular Choreographers of Wound Healing

74 citations , August 2023 in “Frontiers in Immunology”

Fibroblasts are key to wound healing by managing immune cells and forming scar tissue.

research Blank Spots in the Map of Human Skin: The Challenge for Xenotransplantation

August 2023 in “International Journal of Molecular Sciences”

Human skin xenografting could improve our understanding of skin development, renewal, and healing.

Mesenchymal Stem Cells Paracrine Proteins From Three-Dimensional Dynamic Culture System Promoted Wound Healing in Third-Degree Burn Models

research Mesenchymal Stem Cells Paracrine Proteins From Three-Dimensional Dynamic Culture System Promoted Wound Healing in Third-Degree Burn Models

July 2023 in “Bioengineering & translational medicine”

Mesenchymal stem cell proteins in a special gel improved healing of severe burns.

research Fibroblasts and Wound Healing: An Update

146 citations , July 2018 in “Regenerative Medicine”

Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.

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