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GlossaryMonocyte Chemoattractant Protein-1 (CCL2)

signaling protein that attracts monocytes to inflammation sites

Monocyte Chemoattractant Protein-1 (MCP-1), also known as CCL2, is a signaling protein that plays a crucial role in the immune system by attracting monocytes, a type of white blood cell, to sites of inflammation or injury. This protein is important in the body's response to infection and tissue damage, but excessive MCP-1 activity can contribute to chronic inflammatory diseases.

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research Expression of Vascular Endothelial Growth Factor, Apoptosis Inhibitors (Survivin and p16) and CCL27 in Alopecia Areata Before and After Diphencyprone Treatment: An Immunohistochemical Study

58 citations , May 2004 in “British Journal of Dermatology”

Diphenylcyclopropenone treatment helps hair growth in alopecia areata by promoting blood vessel growth and cell survival.

Single-Cell Sequencing Reveals Differential Cell Types in Skin Tissues of Liaoning Cashmere Goats and Key Genes Potentially Related to the Fineness of Cashmere Fiber

research Single-Cell Sequencing Reveals Differential Cell Types in Skin Tissues of Liaoning Cashmere Goats and Key Genes Potentially Related to the Fineness of Cashmere Fiber

3 citations , November 2021 in “Frontiers in Genetics”

Certain genes are linked to the quality of cashmere in goats.

research Overlaps Between Inflammatory Dermatoses and Ichthyoses: Need for Novel Therapeutic Approaches

November 2022 in “Journal of Investigative Dermatology”

Patients with ichthyosis often experience symptoms similar to psoriasis and atopic dermatitis, suggesting that targeted therapies could improve their condition.

research Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice

1533 citations , October 2008 in “Endocrine reviews”

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

research Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle

417 citations , September 2005 in “PLoS biology”

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

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community Aromatase Upregulation along with DHT down regulation could possibly hold the cure

in Microneedling 7 upvotes 3 years ago

The post discusses the potential of upregulating aromatase to treat hair loss, suggesting that increasing CCL2 levels through Vitamin D or microneedling might help. The user questions why microneedling doesn't work for everyone, especially those with advanced hair loss.