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GlossaryCB1 receptor (CB1)

protein in the brain that interacts with cannabinoids

The CB1 receptor, also known as the Cannabinoid receptor type 1, is a protein found primarily in the brain and central nervous system. It plays a crucial role in regulating various physiological processes, including mood, appetite, pain sensation, and memory, by interacting with endocannabinoids and cannabinoids like THC from cannabis.

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research Involvement of Mast Cells and CB1 in the Pathogenesis of IgA Vasculitis

April 2023 in “Journal of Investigative Dermatology”

Mast cells and the CB1 receptor may be key in causing IgA vasculitis.

research Laminin-511 Is a New Player in the Development of Psoriasis and Controlled via Cannabinoid Receptor Type 1

April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

Laminin-511 is involved in psoriasis development and can be regulated by cannabinoid receptor type 1.

Human Epithelial Stem Cell Survival Within Their Niche Requires Tonic Cannabinoid Receptor 1 Signaling—Lessons From the Hair Follicle

research Human Epithelial Stem Cell Survival Within Their Niche Requires Tonic Cannabinoid Receptor 1 Signaling—Lessons From the Hair Follicle

14 citations , February 2021 in “Experimental Dermatology”

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.

research Peer Review of a Novel Control of Human Keratin Expression: Cannabinoid Receptor 1-Mediated Signaling Down-Regulates the Expression of Keratins K6 and K16 in Human Keratinocytes In Vitro and In Situ

February 2013

Activating CB1 can reduce keratin levels, potentially helping manage psoriasis and aid wound healing.

research 17β-Estradiol May Control Human Hair Follicle Growth Also via Up-Regulating the Expression of Cannabinoid Receptor Type 1

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

17β-estradiol may help hair growth by increasing cannabinoid receptor type 1.

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community 2020-2025, progress slowed down and now it’s plateaued

iWillLift in Journals / Progress Pictures 235 upvotes 3 months ago

The user has been using finasteride and topical minoxidil since 2020 with good initial results, but progress has stalled since 2024. They are considering switching to dutasteride and oral minoxidil for better results.

community Will Min work even though it’s been 20 years since I started taking Fin?

rider in General 109 upvotes 1 year ago

The user has been using finasteride for 20 years to stop hair loss and is considering using minoxidil and microneedling to regrow hair on the hairline. They are also open to trying other treatments like hair transplants but prefer less invasive options first.

community Weed/THC effects on hair growth/hair loss, and vitality of organ-culture human follicle studies (research review)

in Research/Science 4 upvotes 1 year ago

Cannabis and THC may have mixed effects on hair, with some studies suggesting potential negative impacts on hair growth in isolated hair follicles, but these results are hard to apply to living humans. Treatments like minoxidil and finasteride are commonly used for hair loss, and the effects of cannabis might be neutral or vary based on individual factors.