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GlossaryCB1 receptor (CB1)

protein in the brain that interacts with cannabinoids

The CB1 receptor, also known as the Cannabinoid receptor type 1, is a protein found primarily in the brain and central nervous system. It plays a crucial role in regulating various physiological processes, including mood, appetite, pain sensation, and memory, by interacting with endocannabinoids and cannabinoids like THC from cannabis.

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research Involvement of Mast Cells and CB1 in the Pathogenesis of IgA Vasculitis

April 2023 in “Journal of Investigative Dermatology”

Mast cells and the CB1 receptor may be key in causing IgA vasculitis.

research Peer Review of a Novel Control of Human Keratin Expression: Cannabinoid Receptor 1-Mediated Signaling Down-Regulates the Expression of Keratins K6 and K16 in Human Keratinocytes In Vitro and In Situ

February 2013

Activating CB1 can reduce keratin levels, potentially helping manage psoriasis and aid wound healing.

research Cannabinoid Signaling in the Skin: Therapeutic Potential of the Cutaneous Cannabinoid System

142 citations , March 2019 in “Molecules/Molecules online/Molecules annual”

Cannabinoids may help treat various skin conditions.

research Endocannabinoids Limit Excessive Mast Cell Maturation And Activation In Human Skin

124 citations , January 2012 in “Journal of Allergy and Clinical Immunology”

Endocannabinoids help control mast cell activity in human skin.

research A Novel Control of Human Keratin Expression: Cannabinoid Receptor 1-Mediated Signaling Down-Regulates the Expression of Keratins K6 and K16 in Human Keratinocytes In Vitro and In Situ

66 citations , February 2013 in “PeerJ”

Activating cannabinoid receptor 1 reduces certain keratin levels, potentially aiding psoriasis treatment.

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community Weed/THC effects on hair growth/hair loss, and vitality of organ-culture human follicle studies (research review)

in Research/Science 5 upvotes 1 year ago

Cannabis and THC may have mixed effects on hair, with some studies suggesting potential negative impacts on hair growth in isolated hair follicles, but these results are hard to apply to living humans. Treatments like minoxidil and finasteride are commonly used for hair loss, and the effects of cannabis might be neutral or vary based on individual factors.