April 2017 in “The Journal of urology/The journal of urology” This study observed that both dutasteride and finasteride affected penile morphology in normotensive and hypertensive rats, with more pronounced changes in hypertensive animals, especially when treated with dutasteride.
June 2018 in “The Journal of Sexual Medicine” This study used high-resolution ultrasound to investigate the pathophysiology of persistent erectile dysfunction in young men who used the drug finasteride, observing differences in erectile tissue homogeneity compared to control subjects without finasteride exposure.
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January 2018 in “Asian Journal of Andrology” Researchers observed that dutasteride and finasteride caused structural changes in the penises of both control and hypertensive rats, with dutasteride having a more pronounced effect on the corpus cavernosum.
This article reviews the role of hormones in human penis development and associated conditions due to hormonal imbalances, but reports no new findings, suggesting hormone replacement can manage some conditions.
December 2016 in “The Journal of Sexual Medicine” This study found that young men using finasteride for androgenic alopecia experienced erectile dysfunction and signs of erectile tissue fibrosis, alongside symptoms like low libido and mood changes.