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research The value of Trichoscopy and Histopathology in the diagnosis of post-COVID-19 telogen effluvium

May 2026 in “Skin Appendage Disorders”

This study identified distinct trichoscopic and histopathological features of telogen effluvium following COVID-19 infection, with trichoscopic vascular patterns correlating with the severity of the initial infection.

research `Cyclic alopecia' inMsx2mutants: defects in hair cycling and hair shaft differentiation

158 citations , December 2002 in “Development”

In this study, Msx2-deficient mice showed progressive hair loss due to shortened anagen phase and prolonged catagen and telogen phases, resulting in cyclic alopecia with structurally abnormal hair shafts.

research In Vivo Non-Invasive Observation of Dynamic Changes in Hair Shaft, Melanin, and Collagen During the C57BL/6 Follicle Cycle

September 2025 in “bioRxiv (Cold Spring Harbor Laboratory)”

In this study, researchers developed non-invasive methods to monitor hair shaft, melanin, and collagen dynamics in C57BL/6 mice across different hair follicle cycle phases, supporting non-invasive research in hair loss treatment development.

research A comparative study of histopathologic features in alopecia areata and pattern hair loss

January 2023 in “Journal of Cutaneous Pathology”

This study found that histopathologic features such as a catagen/telogen shift, melanin in fibrous tracts, and small dystrophic follicles can help differentiate alopecia areata from pattern hair loss in the absence of peribulbar infiltrates.

research Healthy Hair: Form and Function

January 2015 in “Springer eBooks”

Hair health is influenced by genetics, aging, and environmental factors, with proper care needed to maintain it.

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community Hair loss over a year following depression and taking antidepressants

in Side effects? 200 upvotes 8 months ago

A 33-year-old experienced significant hair loss after a depressive episode and taking paroxetine, possibly due to telogen effluvium or androgenic alopecia. Suggestions included reducing alcohol, considering finasteride and minoxidil, and consulting a doctor about antidepressant side effects.

community PP405 Won’t Work: Follicle Is Miniaturized, Fibrosed, And Missing Key Support Cells

7 months ago

PP405 is ineffective for miniaturized, fibrosed hair follicles in androgenetic alopecia. AMP303 may activate hair follicle stem cells, but minoxidil and finasteride are still the main treatments.

community My Theory Of Androgenic Alopecia

16 upvotes 10 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

211 upvotes 1 year ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

community Prolactin the Cause of Hair Loss? ABS-201 the Cure?

29 upvotes 2 months ago

Prolactin may contribute to hair loss, but targeting its receptor won't cure androgenetic alopecia. ABS-201 could be a useful alternative or adjuvant therapy, similar to JAK inhibitors, but not more effective than HMI-115.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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research The value of Trichoscopy and Histopathology in the diagnosis of post-COVID-19 telogen effluvium

research `Cyclic alopecia' inMsx2mutants: defects in hair cycling and hair shaft differentiation

research In Vivo Non-Invasive Observation of Dynamic Changes in Hair Shaft, Melanin, and Collagen During the C57BL/6 Follicle Cycle

research A comparative study of histopathologic features in alopecia areata and pattern hair loss

research Healthy Hair: Form and Function

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community Hair loss over a year following depression and taking antidepressants

community PP405 Won’t Work: Follicle Is Miniaturized, Fibrosed, And Missing Key Support Cells

community My Theory Of Androgenic Alopecia

community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

community Prolactin the Cause of Hair Loss? ABS-201 the Cure?

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