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Transgenic Erythropoietin Overexpression Inhibits Dermal Fat Formation and HIF1a in the Skin and Causes Telogen Effluvium in Mouse Pups During the First Hair Cycle

research 2063-LB: Transgenic Erythropoietin Overexpression Inhibits Dermal Fat Formation and HIF1a in the Skin and Causes Telogen Effluvium in Mouse Pups during the First Hair Cycle

June 2024 in “Diabetes”

This study found that overexpression of erythropoietin disrupted hair growth in mice by affecting dermal fat lipogenesis and lipolysis, leading to poor hair follicle development and truncal alopecia.

research From Telogen to Exogen: Mechanisms Underlying Formation and Subsequent Loss of the Hair Club Fiber

81 citations , April 2009 in “Journal of Investigative Dermatology”

This review discusses the shedding phase of the hair cycle, known as exogen, and reports no new findings while analyzing related processes like club fiber formation and release.

research Basonuclin as a cell marker in the formation and cycling of the murine hair follicle

27 citations , October 1998 in “Differentiation”

Basonuclin helps identify and track hair follicle development and cycling in mice.

research Basonuclin as a cell marker in the formation and cycling of the murine hair follicle

January 1998 in “Differentiation”

Basonuclin is crucial for hair follicle development and cycling in mice.

The Overexpression of R-Spondin 3 Affects Hair Morphogenesis and Development Along with the Formation and Maturation of Hair Follicle Stem Cells

research The overexpression of R-spondin 3 affects hair morphogenesis and hair development along with the formation and maturation of the hair follicle stem cells

6 citations , September 2024 in “Frontiers in Physiology”

This study found that overexpression of R-spondin 3 in a mice model impaired hair morphogenesis and regeneration by reducing hair matrix progenitor cell proliferation, thus disrupting the Wnt pathway's regulation of stem cells.

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Community Join

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community Making your own RT1640 in China

4 years ago

RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

community Bryan Johnson's email regarding hair loss and his protocol (including why he doesn't take Fin or Dut).

in Research/Science 6 upvotes 5 months ago

Hair loss treatments include topical and oral minoxidil, low-level laser light therapy, and peptide serums. Bryan Johnson avoids finasteride and dutasteride due to potential side effects, focusing instead on his own protocol with these treatments.

community The Real Cause Of Androgenetic Alopecia

675 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community My derm said they came up with a new serum that is better then fin? What’s y’all’s thoughts

7 months ago

A new serum claims to enhance hair regrowth by amplifying oxygen delivery, improving the effectiveness of treatments like exosomes and peptides. Users are skeptical, questioning its efficacy compared to established treatments like Minoxidil and Finasteride.

community Finally, some real breakthroughs. A comparison of the two leading baldness treatments: PP405 versus ABS-201

106 upvotes 10 months ago

PP405 and ABS-201 are promising treatments for male pattern baldness. PP405 shows rapid hair growth in human trials, while ABS-201 shows significant regrowth in animal studies but is still in early human trials.

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Learn

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learn Thymosin Beta 4

learn sh-Polypeptide-7

learn Beta Polypeptide

learn Vascular Endothelial Growth Factor

learn Epidermal Growth Factor

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