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GlossaryCardiotoxicity

damage to heart muscle from certain drugs or toxins

Cardiotoxicity refers to the damage that certain substances, such as chemotherapy drugs or toxins, can cause to the heart muscle. This damage can lead to a range of heart problems, including arrhythmias (irregular heartbeats), heart failure, and reduced heart function. For professionals, monitoring for cardiotoxicity is crucial when administering treatments known to have potential cardiac side effects, as early detection can help mitigate long-term damage.

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Reduced Cardiotoxicity and Comparable Efficacy in a Phase III Trial of Pegylated Liposomal Doxorubicin HCl (CAELYX/Doxil) Versus Conventional Doxorubicin for First-Line Treatment of Metastatic Breast Cancer

research Reduced Cardiotoxicity and Comparable Efficacy in a Phase III Trial of Pegylated Liposomal Doxorubicin HCl (CAELYX/Doxil) Versus Conventional Doxorubicin for First-Line Treatment of Metastatic Breast Cancer

1461 citations, March 2004 in “Annals of oncology”

Pegylated liposomal doxorubicin is as effective as conventional doxorubicin but causes fewer heart problems and side effects.

research Cardiac Morphologic Alterations in Acute Minoxidil Cardiotoxicity in Miniature Swine

27 citations, August 1984 in “Experimental and Molecular Pathology”

research Age Dependence of the Cardiac Lesions Induced by Minoxidil in Rats

23 citations, June 1996 in “Toxicology”

Older rats more affected by minoxidil's cardiotoxic effects than younger rats.

research Hypertrichosis Due to Minoxidil

45 citations, November 1979 in “British Journal of Dermatology”

Minoxidil causes excessive hair growth in almost all patients.

research Cardioprotective Effect of Royal Jelly on Paclitaxel-Induced Cardiotoxicity in Rats

24 citations, February 2016 in “PubMed”

Royal jelly can protect the heart from damage caused by paclitaxel.

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community Have to share with you guys. I’m 41. Can’t believe this is actually working. I was bald as hell 1 year ago. I have a ways to go still. Pics of all products included. Most purchased on Amazon

in Progress Pictures 1315 upvotes 7 months ago

A user shared their successful hair regrowth using a combination of derma stamping, Retinol, Minoxidil, Dutasteride, and RU58841, with no side effects. Others discussed their varied experiences with these treatments, including concerns about potential side effects like heart issues and sexual dysfunction.

community Anyone on 1mg Dutasteride daily (or more)?

in Finasteride/Dutasteride 18 upvotes 4 months ago

The conversation discusses using 1mg Dutasteride daily for hair loss and its effects on hair, acne, and body hair. One user mentions that shedding hair can be a positive sign of new hair growth.

community drinking topical minoxidil – extreme hair growth everywhere

in Minoxidil 396 upvotes 2 years ago

At this point. In this conversation, users discussed the risks of drinking topical minoxidil and suggested alternative treatments such as obtaining a prescription for oral minoxidil or finasteride.

community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 122 upvotes 6 months ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community What’s your nuclear protocol???

in Chat 19 upvotes 1 year ago

People discussed their intense hair loss treatments, including the use of dutasteride, RU58841, minoxidil, tretinoin, essential oils, microneedling, and various topical sprays. Some users reported success with these methods in preventing hair loss and stimulating hair growth.

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