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In this animal study, researchers found that exposure to a CO2 laser at various power levels caused significant skin damage in rats, including severe burns, coagulation, and tissue obliteration, with higher laser doses resulting in more pronounced injuries.

This study investigated the effects of 10600nm CO2 dot laser and Nd: YAG laser on Wistar rats' skin, finding that CO2 laser treatment resulted in higher positive expression of MMP-1 and TIMP-1 compared to Nd: YAG laser, with statistically significant differences noted.

Carbon dioxide laser treatment effectively removed facial hair cysts without scarring or them coming back.

This case report describes a therapy-resistant folliculitis decalvans patient who showed nearly complete response with increased hair density after treatment with CO2 laser-assisted photodynamic therapy.

This case report observed that resection of a lesion using a carbon-dioxide laser in a Labrador retriever with lingual hair heterotopia led to positive outcomes, although hair partially regrew.