15 citations
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July 2019 in “Journal of Biological Inorganic Chemistry” This study found that finasteride effectively prevented testosterone-induced kidney stone formation in renal tubular cells by reducing COM crystal adhesion and crystallization.
January 2025 in “The Analyst” In this study, researchers identified a novel biomarker of oxalate metabolism, which plays a crucial role in conditions like hyperoxaluria and kidney stones, marking the first time this detection has been reported.
November 2025 in “Contact Dermatitis” This study reported a case of acute kidney injury and toxic contact dermatitis in a 25-year-old woman following exposure to a glyoxylic acid-containing hair straightening product, highlighting glyoxylic acid's potential role in cutaneous and renal complications and underscoring the need for stronger regulation and awareness.
October 2025 in “Nephrology Dialysis Transplantation” In this case report, a young woman experienced acute kidney injury linked to the use of a hair straightening product containing glyoxylic acid, suggesting dermal absorption may lead to calcium oxalate nephropathy; this highlights the need for regulatory review and public health intervention.
August 2025 in “Clinical Toxicology” This study suggests an association between glyoxylic acid-containing hair-straightening treatments and acute kidney injury in young women, with urine calcium oxalate crystals observed in some cases, indicating potential nephrotoxicity. Early treatment with thiamine and pyridoxine may mitigate the severity of kidney damage.