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This study found that redhaired individuals consistently had higher calcidiol levels compared to non-redhaired subjects, suggesting a physiological adaptation for vitamin D synthesis in low UV-B conditions.

This study found that redhaired individuals exhibit higher calcidiol levels compared to non-redhaired individuals, suggesting a possible evolutionary adaptation for vitamin D photosynthesis in low UV-B environments in Europe.

This study identified three new mutations in the VDR ligand-binding domain that may cause dysfunction, and noted that oral calcium and calcidol treatment was effective, but only one patient experienced hair growth.

This study suggests that there is a U-shaped relationship between vitamin D hormonal forms and aging, with an optimal serum calcidiol concentration needed to minimize aging-related chronic disease risk.

This study found that redheaded individuals had higher levels of vitamin D precursor 25(OH)D3 compared to non-redheaded individuals, suggesting a physiological adaptation to low UVB radiation in Europe.