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Epoxy Fatty Acids and Inhibition of the Soluble Epoxide Hydrolase Selectively Modulate GABA Mediated Neurotransmission to Delay Onset of Seizures

research Epoxy Fatty Acids and Inhibition of the Soluble Epoxide Hydrolase Selectively Modulate GABA Mediated Neurotransmission to Delay Onset of Seizures

60 citations , December 2013 in “PLoS ONE”

EETs can delay seizures by affecting GABA activity, offering potential new treatments for seizures.

research The Urine as a Diagnostic Key for a Homozygous EGFR Mutation

2 citations , March 2022 in “Portuguese Journal of Nephrology & Hypertension”

A rare EGFR mutation in newborns leads to severe health issues and early death.

research The Many Faces of Calcineurin Inhibitor Toxicity—What the FK?

97 citations , January 2020 in “Advances in chronic kidney disease”

Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.

research Dynamics of Actin Filaments Play an Important Role in Root Hair Growth Under Low Potassium Stress in Arabidopsis Thaliana

August 2024 in “International Journal of Molecular Sciences”

Actin filaments help root hairs grow faster and longer under low potassium stress.

research Exploring the Neural Mechanisms of Finasteride: A Proteomic Analysis in the Nucleus Accumbens

14 citations , October 2016 in “Psychoneuroendocrinology”

Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.

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community Progress pictures. 2 months on Fin, 4 on Min.

in Progress Pictures 191 upvotes 1 year ago

The user experienced significant hair regrowth after using Finasteride for 2 months and Minoxidil for 4 months, along with a derma roller. They reported no side effects from the treatments and noted that Finasteride seemed to contribute most to the progress.

community Eliminating scalp itch leads to regrowth (and my RU58841 progress)

in Research/Science 64 upvotes 2 years ago

User experienced hair regrowth after eliminating scalp itch with RU58841. Others discussed itch and hair loss connection, and effectiveness of combining RU58841 with 5AR inhibitors.

community DHT Harms Scalp Microbiome: DHT Itch is REAL

in Research/Science 409 upvotes 9 months ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community Meta analysis of minoxidil only vs 5AR inhibitors

in Research/Science 58 upvotes 8 months ago

Oral dutasteride is the most effective for hair regrowth, followed by oral finasteride and minoxidil. Topical finasteride combined with minoxidil is recommended for those avoiding systemic DHT reduction.

community Serious question, is there nothing that can be done if Dutasteride doesn’t help to stop my hair loss?

in Finasteride/Dutasteride 61 upvotes 3 years ago

A 25 year old male who has been using finasteride and dutasteride for two years to treat his hair loss, with no success. Other treatments such as oral minoxidil, topical anti-androgens, RU58841, latanoprost, topical estrogen, CB 03 01, microneedling, keto 2% shampoo, vitamin D, Omega 3, B vitamins and probiotics were discussed.

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