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Mechanism of Action of Minoxidil Sulfate-Induced Vasodilation: A Role for Increased Potassium Permeability

research Mechanism of action of minoxidil sulfate-induced vasodilation: a role for increased K+ permeability.

48 citations , June 1988 in “PubMed”

In this study, minoxidil sulfate was found to relax norepinephrine-induced contractions in rabbit mesenteric arteries, possibly by acting as a K+ channel agonist, but it did not relax K+-induced contractions.

research Hair-growth as anti-aging

1 citations , January 2009 in “Drug delivery system”

This article provides a detailed review of minoxidil's pharmacological effects for treating androgenic alopecia but reports no new clinical results.

research Concentration homeostasis and elements in hair and dried serum observed by X-ray fluorescence analysis using synchrotron radiation

5 citations , July 2014 in “Journal of X-Ray Science and Technology”

This study suggests that hair analysis could serve as a diagnostic tool for detecting calcium channel activity, which influences hair calcium levels and may indicate calcium deficiency or related disease states.

research Molecular insights into the formation of drug-polymer inclusion complex

October 2023

This study reports that carbamazepine can self-assemble into stable channel structures without guest polymers, while griseofulvin relies on guest molecules for structural stability in drug-polymer inclusion complexes.

research The incidental pore: Ca_V1.2 and stem cell activation in quiescent hair follicles

3 citations , June 2013 in “Genes & development”

In their research, Yucel and colleagues found that CaV1.2 is expressed in hair follicle stem cells, facilitating anagen re-entry in a way not dependent on calcium flux.

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Community Join

5 / 166 results

community Progress pictures. 2 months on Fin, 4 on Min.

in Progress Pictures 191 upvotes 1 year ago

The user experienced significant hair regrowth after using Finasteride for 2 months and Minoxidil for 4 months, along with a derma roller. They reported no side effects from the treatments and noted that Finasteride seemed to contribute most to the progress.

community Eliminating scalp itch leads to regrowth (and my RU58841 progress)

63 upvotes 3 years ago

User experienced hair regrowth after eliminating scalp itch with RU58841. Others discussed itch and hair loss connection, and effectiveness of combining RU58841 with 5AR inhibitors.

community Meta analysis of minoxidil only vs 5AR inhibitors

in Research/Science 58 upvotes 1 year ago

Oral dutasteride is the most effective for hair regrowth, followed by oral finasteride and minoxidil. Topical finasteride combined with minoxidil is recommended for those avoiding systemic DHT reduction.

community DHT Harms Scalp Microbiome: DHT Itch is REAL

413 upvotes 1 year ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community Serious question, is there nothing that can be done if Dutasteride doesn’t help to stop my hair loss?

60 upvotes 4 years ago

A 25 year old male who has been using finasteride and dutasteride for two years to treat his hair loss, with no success. Other treatments such as oral minoxidil, topical anti-androgens, RU58841, latanoprost, topical estrogen, CB 03 01, microneedling, keto 2% shampoo, vitamin D, Omega 3, B vitamins and probiotics were discussed.

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