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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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research Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5-Alpha-Reductase Inhibitors
Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.
research 5α-Reductase Inhibitors: Chemical and Clinical Models
Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.
research Selective Non-Steroidal Inhibitors of 5α-Reductase Type 1
Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.
research Screening of Synthetic and Natural Product Databases: Identification of Novel Androgens and Antiandrogens
Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.
research Design, Synthesis, and Structure-Activity Relationship Studies on Steroidal Aromatase and 5α-Reductase Inhibitors as Anti-Tumor Agents
Modified steroidal inhibitors showed promise in treating hormone-dependent cancers.
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5 / 783 resultscommunity 21 y/o M, 3 month amazing progress on min and topical fin, I want to share my success story.
A 21-year-old male who has been suffering from hair loss since he was 17, and has made great progress with a combination of minoxidil and finasteride topical solutions. They discussed the efficacy of microneedling for sensitive scalps as well.
community If the big duo don’t work Time to give up?
If oral minoxidil 2.5mg and finasteride 1mg fail after a year, some suggest trying dutasteride. Hair shedding can be normal in the first year, and real changes often occur between 9 months to a year.
community Countering oral minoxidil side effects by taking collagen supplements?
Oral minoxidil may deplete collagen, potentially causing skin aging. Users discuss whether taking collagen supplements can counteract this effect.
community Medication plan after hair transplant - advice on timing finasteride & oral minoxidil (indoor cat; work with pregnant women)
The user plans to start 1 mg finasteride immediately and oral minoxidil two months later after a hair transplant, considering potential side effects and exposure risks. They seek advice on timing due to concerns about shedding before their wedding.
community Carnitine Tartrate + Potassium chloride + Niacin
The post discusses using Carnitine Tartrate, Potassium Chloride, and Niacin to reduce hair shedding, with the user experiencing significant improvement. The user also suggests considering a ketogenic/paleo diet for those with insulin resistance-related hair loss.