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research Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5-Alpha-Reductase Inhibitors
Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.
research 5α-Reductase Inhibitors: Chemical and Clinical Models
Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.
research Design, Synthesis, and Structure-Activity Relationship Studies on Steroidal Aromatase and 5α-Reductase Inhibitors as Anti-Tumor Agents
Modified steroidal inhibitors showed promise in treating hormone-dependent cancers.
![Effect of C-Ring Modifications in Benzo[c]quinolizin-3-ones, New Selective Inhibitors of Human 5α-Reductase 1](/images/research/c687900f-ea40-4de1-8f0b-a5b818951b1c/small/15452.jpg)
research Effect of C-Ring Modifications in Benzo[c]quinolizin-3-ones, New Selective Inhibitors of Human 5α-Reductase 1
Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.
research Effect of Solvent on Stereoselectivity in Pd/C (Type 39K)-Catalyzed Hydrogenation of Methyl 3-Oxo-4-Aza-5-Androstene-17-Carboxylate, a Key Intermediate for Finasteride and Dutasteride
Alcoholic solvent improves selectivity in key intermediate for finasteride and dutasteride synthesis.
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5 / 772 resultscommunity 21 y/o M, 3 month amazing progress on min and topical fin, I want to share my success story.
A 21-year-old male who has been suffering from hair loss since he was 17, and has made great progress with a combination of minoxidil and finasteride topical solutions. They discussed the efficacy of microneedling for sensitive scalps as well.
community Balding at the age of 17 years old
A 17-year-old experiencing hair loss is using Minoxidil but is hesitant about Finasteride due to potential side effects. Others recommend Finasteride for its effectiveness and suggest alternatives like vitamins and derma rollers.
community Pls advice needed. 17-20 yo. Not seeing the progress I hoped for on finasteride + minoxidil. Any advice?
A user is experiencing hair loss despite using topical minoxidil, oral finasteride, and 2% ketoconazole shampoo, and is seeking advice on further treatments. Suggestions include switching to dutasteride, trying oral minoxidil, addressing scalp inflammation, and considering dietary changes and supplements.
community How Veradermics secured a total of $220 million in series B and C financing for oral minoxidil, I will never understand.....
Veradermics' oral minoxidil shows promise for hair regrowth, with some users reporting significant improvements, while Pelage's PP405 results are less convincing and lack transparency. There is skepticism about both treatments' long-term effectiveness and potential side effects.
community 17M Concerned About Thinning on Back and Crown, Unable to See Dermatologist for a Year
A 17-year-old is concerned about hair thinning and unable to see a dermatologist for a year. They are advised to consider using topical minoxidil and possibly finasteride in the future.