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research Alopecia in a Viable Phospholipase C Delta 1 and Phospholipase C Delta 3 Double Mutant

8 citations , June 2012 in “PloS one”

This study found that the Plcd3(mNab) mutation in mice worsens the alopecia caused by Plcd1 loss, suggesting synergistic effects between Plcd1 and Plcd3 on hair follicle health.

research Syndromic epidermolysis bullosa simplex subtype due to mutations in the KLHL24 gene: series of case reports in Russian families

3 citations , July 2024 in “Frontiers in Medicine”

This study reports that analyzing the clinical manifestations of different genetic variants in EBS families helps predict disease progression and severity, guide complication risk assessment, and plan necessary medical care.

research Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity

70 citations , August 2006 in “Cancer Research”

This study found that inhibiting AP-1 activity in mice modified tumor development, leading to transdifferentiation between squamous and sebaceous tumors, with molecular analysis suggesting AP-1's role in maintaining tumor cell identity.

research Intrinsic ROS Drive Hair Follicle Cycle Progression by Modulating DNA Damage and Repair and Subsequently Hair Follicle Apoptosis and Macrophage Polarization

20 citations , January 2022 in “Oxidative Medicine and Cellular Longevity”

This study found that intrinsic reactive oxygen species drive the hair follicle cycle progression through DNA damage and repair, apoptosis, and macrophage polarization, influencing hair loss and regeneration dynamics in mice.