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GlossaryBusulfan

chemotherapy drug used to treat certain cancers

Busulfan is a chemotherapy drug primarily used to treat certain types of cancer, such as chronic myelogenous leukemia (CML). It works by interfering with the DNA inside cancer cells, preventing them from growing and dividing. However, it can also cause side effects like hair loss (alopecia) and damage to bone marrow, which is why its use is carefully monitored by healthcare professionals.

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Comparison of Allogeneic Stem Cell Transplant Conditioning Regimens in AML, MDS, and CLL

research Comparison of Allogeneic Stem Cell Transplant Conditioning Regimens in AML, MDS, and CLL

January 2018 in “General internal medicine and clinical innovations”

Busulfan/cyclophosphamide and total bone irradiation are equally effective for AML transplants.

research Six Cases of Permanent Alopecia After Various Conditioning Regimens Commonly Used in Hematopoietic Stem Cell Transplantation

40 citations , September 2007 in “Bone marrow transplantation”

Certain chemotherapy drugs can cause permanent hair loss in stem cell transplant patients.

Priming Mobilization of Hair Follicle Stem Cells Triggers Permanent Loss of Regeneration After Alkylating Chemotherapy

research Priming Mobilization of Hair Follicle Stem Cells Triggers Permanent Loss of Regeneration After Alkylating Chemotherapy

32 citations , August 2019 in “Nature Communications”

Chemotherapy causes permanent hair follicle damage by triggering stem cell loss.

Clinical and Histological Study of Permanent Alopecia After Bone Marrow Transplantation

research Clinical and Histological Study of Permanent Alopecia After Bone Marrow Transplantation

23 citations , December 2015 in “Anais Brasileiros de Dermatologia”

Permanent hair loss after bone marrow transplant can be caused by chemotherapy or chronic graft-versus-host disease.

Radiation- and Chemotherapy-Induced Permanent Alopecia: Case Series

research Radiation- and Chemotherapy-Induced Permanent Alopecia: Case Series

14 citations , January 2013 in “Journal of Cutaneous Medicine and Surgery”

Some cancer treatments can cause permanent hair loss.

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