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research Brief Report: Requirement of TACE/ADAM17 for Hair Follicle Bulge Niche Establishment

14 citations , June 2012 in “Stem Cells”

This study found that depletion of TACE in mouse hair follicles led to impaired stem cell maintenance and hair loss, implicating TACE and EGFR signaling in hair follicle stem cell homeostasis.

research Cellular dynamics in the niche of infrequently dividing hair follicle stem cells in the mouse Mus musculus

October 2010 in “eCommons (Cornell University)”

This study found that mouse hair follicle stem cells use symmetric cell division for maintenance and fate determination, and identified Gata6 as a crucial factor for their differentiation.

research Synergy of understanding dermatologic disease and epidermal biology

10 citations , February 2012 in “Journal of Clinical Investigation”

This review discusses advancements in understanding the biology and pathology of the epidermis and hair follicles, reporting no new clinical results but highlighting the synergy between research and dermatologic patient care.

research Epidermal homeostasis: a balancing act of stem cells in the skin

1039 citations , February 2009 in “Nature Reviews Molecular Cell Biology”

This review discusses the reuse of molecular mechanisms involved in embryonic skin development for maintaining adult epidermal homeostasis and reports no new results.

research Perivascular Hair Follicle Stem Cells Associate with a Venule Annulus

51 citations , April 2013 in “Journal of Investigative Dermatology”

Hair follicle stem cells rely on nearby blood vessels for their maintenance and function.

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Community Join

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community DHT Isn’t the Only Factor in Hair Loss and That Might Be the Key to a Real Cure

373 upvotes 6 months ago

Hair loss involves more than just DHT, with genetic factors like TRPS affecting hair follicles. Treatments such as Amplifica's AMP-601 and AMP-303 target stem cells for potential hair growth solutions.

community A Theory on Why Microneedling Works

175 upvotes 6 years ago

Microneedling may enhance hair regrowth by transferring stem cells to dormant follicles, improving the effects of minoxidil. Users discuss using microneedling with needle lengths around 1.5mm to stimulate hair growth.

community Y'all, we have got to come to a consensus on the specifics of microneedling.

27 upvotes 4 years ago

Microneedling can promote hair growth, but there is uncertainty about the best practices, including needle length, device, and session frequency. Users discuss using needle lengths between 0.5mm and 1.5mm, with some experiencing pinpoint bleeding, and emphasize the need for more reliable resources and guidelines.

community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

67 upvotes 11 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

community A Nuanced Look at Microdosing Topical Finasteride

86 upvotes 2 years ago

The conversation discusses using a low dose of topical finasteride to achieve hair benefits with minimal systemic exposure. Users share experiences and opinions on dosing, systemic buildup, and side effects of both topical and oral finasteride.

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Learn

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learn Stem Cell Factor

learn Thymosin Beta 4

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