72 citations
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July 2012 in “Journal of Investigative Dermatology” This study found that mice with a specific loss of DNA methyltransferase 1 showed uneven epidermal thickness, reduced hair regeneration, and progressive alopecia, emphasizing DNA methylation's role in stem cell homeostasis.
3 citations
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December 2022 in “Nutrients” This study found that limonin may promote hair growth by enhancing anagen signaling through autophagy activation in rat dermal papilla cells, suggesting its potential as a natural treatment for hair loss.
31 citations
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August 2000 in “Journal of Investigative Dermatology” This study found that when human hair follicles were grafted onto mice, they progressed through dystrophic stages and returned to normal growth, with stem cells aiding in recovery.
24 citations
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December 2014 in “International Journal of Molecular Medicine” In this study, researchers found that petroleum ether extract of Eclipta alba significantly stimulated follicular keratinocyte proliferation and reduced TGF-β1 expression in nude mice, suggesting potential use for certain types of alopecia.
January 2009 in “Heilongjiang xumu shouyi” This study found that BrdU labeling in Inner Mongolia cashmere goats revealed the presence and localization of stem cells in primary and secondary hair follicles and the epidermis, with signals diminishing after 10 weeks.