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GlossaryBone Morphogenetic Protein 7 (BMP7)

promotes bone and cartilage development and repair

Bone Morphogenetic Protein 7 (BMP7), also known as Osteogenic Protein 1 (OP-1), is a protein that plays a crucial role in the development of bone and cartilage. It is part of the transforming growth factor-beta (TGF-β) superfamily and is involved in the regulation of cell growth, differentiation, and repair, making it important for both developmental biology and potential therapeutic applications in conditions like bone fractures and osteoarthritis.

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BMP2 And BMP7 Play Antagonistic Roles In Feather Induction

research BMP2 And BMP7 Play Antagonistic Roles In Feather Induction

88 citations , July 2008 in “Development”

BMP2 and BMP7 have opposite roles in feather formation.

research The Role of BMP7 in the Proliferation of Hu Sheep Dermal Papilla Cells Is Influenced by DNA Methylation

June 2024 in “Animals”

DNA methylation affects BMP7 gene expression, influencing cell growth in Hu sheep.

Identification of a Secreted BMP Antagonist, Ectodin, Integrating BMP, FGF, and SHH Signals from the Tooth Enamel Knot

research Identification of a Secreted BMP Antagonist, Ectodin, Integrating BMP, FGF, and SHH Signals from the Tooth Enamel Knot

243 citations , October 2003 in “Developmental biology”

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

Morpho-Regulation of Ectodermal Organs

research Morpho-Regulation of Ectodermal Organs

131 citations , March 2004 in “The American journal of pathology”

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

research Transcriptome Reveals Long Non-Coding RNAs and mRNAs Involved in Primary Wool Follicle Induction in Carpet Sheep Fetal Skin

37 citations , May 2018 in “Frontiers in physiology”

Certain RNA molecules are important for the development of wool follicles in sheep.

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