291 citations
,
October 2005 in “Proceedings of the National Academy of Sciences of the United States of America”
This study found that rat whisker follicle stem cells can be expanded in culture and transplanted to form functional hair follicles, demonstrating their multipotency and potential for regenerative medicine.
62 citations
,
April 2009 in “British Journal of Dermatology”
This review discusses the potential markers for identifying and studying stem cells in the epidermis and hair follicles, highlighting their role in understanding skin disease pathogenesis and expanding therapeutic options, but reports no new findings.
1 citations
,
September 2017 in “Journal of Investigative Dermatology”
This study reported that introducing the TERT and Bmi1genes into mouse dermal papilla cells resulted in immortal cells capable of inducing new hair follicles in vivo, and human immortal DPCs were also developed.
4 citations
,
May 2023 in “Pigment Cell & Melanoma Research”
In this study, researchers found that deleting the Bmi1gene in murine melanocytes caused premature hair greying and loss of melanocyte lineage cells, highlighting BMI1's role in protecting melanocyte stem cells from stress and oxidative damage.