research Clock genes, hair growth and aging
This study found that circadian clock genes are involved in regulating the hair growth cycle, suggesting a connection between daily rhythms and the longer hair follicle cycling process.
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research Local circadian clock gates cell cycle progression of transient amplifying cells during regenerative hair cycling
This study discovered that the circadian clock influences hair follicle regeneration, making hair grow faster in the morning and causing more radiation-induced hair loss in the morning compared to the evening.
research Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival
This study found that many effects previously thought to be caused by circadian rhythm disruption in Bmal1 knockout mice are actually due to BMAL1's properties unrelated to its clock function.
research Premature aging and cancer development in transgenic mice lacking functional CYLD
This study found that transgenic mice expressing a mutant CYLD protein lacking deubiquitinase function showed signs of premature aging and spontaneous tumor development, likely due to over-activation of specific molecular pathways and chronic inflammation.
research The clock gene brain and muscle Arnt-like protein-1 (BMAL1) is involved in hair growth
This study concluded that the expression of clock genes, specifically BMAL1, in hair follicles is linked to circadian rhythm, and BMAL1 regulates hair growth.
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