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May 2025 in “Archives of Dermatological Research” This study found that microinfusion of 0.5% minoxidil in the scalp led to a significant reduction in diastolic blood pressure, indicating systemic absorption, while the control group experienced a rise in systolic pressure possibly due to procedural pain.
October 2023 in “Journal of The American Academy of Dermatology” This article discusses the use of low-dose oral minoxidil as an off-label treatment for androgenetic alopecia but reports no new clinical results.
April 2025 in “Research Square (Research Square)” This study found that microinfusion of minoxidil into the scalp was associated with a reduction in diastolic blood pressure, indicating systemic absorption of the drug.
May 2024 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Oral minoxidil 7.5 mg for hair loss increases heart rate but not blood pressure.
July 2025 in “Journal of Investigative Dermatology” Spironolactone can safely lower blood pressure in patients on other blood pressure medications, but may slightly increase the risk of low blood pressure.