Search

for
Search:

Research

5 / 1000+ results

research Fetal Fibroblast Heterogeneity Defines Dermal Architecture during Human Embryonic Skin Development

8 citations , January 2025 in “Journal of Investigative Dermatology”

In this study, researchers analyzing human fetal skin fibroblasts found eight distinct populations with developmental stage-specific abundance, identifying markers linked to fibroblast functions in blood vessel development, dermal layers, and hair follicle maturation.

research Distinct Fibroblast Lineages Give Rise to NG2+ Pericyte Populations in Mouse Skin Development and Repair

37 citations , May 2021 in “Frontiers in Cell and Developmental Biology”

This study found that Ng2+ perivascular cells in mouse skin are a diverse lineage-restricted population primarily recruited from papillary or reticular fibroblast lineages during wound healing, maintaining heterogeneity in both wounded and non-wounded skin.

research Development of a Chitosan Nanofibrillar Scaffold for Skin Repair and Regeneration

162 citations , July 2011 in “Biomacromolecules”

This study found that chitosan nanofibrillar scaffolds accelerated skin wound healing in mice by enhancing cell adhesion, proliferation, and regeneration of epidermis and dermis compared to other forms.

Development and Characterization of Polydeoxyribonucleotide Loaded Chitosan Polyplex for Wound Healing

research Development and characterization of polydeoxyribonucleotide (PDRN) loaded chitosan polyplex: In vitro and in vivo evaluation of wound healing activity

September 2023 in “International journal of biological macromolecules”

This study found that a chitosan/PDRN nanopolyplex significantly improved diabetic wound healing in rats by enhancing cell proliferation, migration, and antimicrobial activities, suggesting its potential as a therapeutic product.

research Organ regeneration based on developmental biology: past and future

21 citations , June 2018 in “Current Opinion in Genetics & Development”

This review discusses recent advancements in regenerative medicine, including functional organ regeneration and the creation of mini-organs, and reports no new clinical results.

View more "blood vessel development" in research →

Community Join

5 / 1000+ results

community A new study by Deng and colleagues set out to explore differences between balding and non balding scalps...

39 upvotes 4 years ago

Balding scalps have more androgen receptors, leading to increased TGF-beta, which causes blood vessel loss and hair follicle miniaturization. Blocking androgen signaling and TGF-beta may help prevent hair loss.

community Interesting discovery in the news?

4 upvotes 2 years ago

A naturally occurring sugar, 2-deoxy-D-ribose, may promote hair growth by forming new blood vessels. There is skepticism about its effectiveness and concerns about potential side effects, with some users comparing it to existing treatments like Minoxidil and finasteride.

community P-1075: a BETTER version of Minoxidil

11 months ago

P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

community How is this even possible that there is no cure till now

in Technology 155 upvotes 4 months ago

There is no permanent cure for hair loss; treatments like finasteride, minoxidil, and hair transplants require ongoing use and are not universally effective. Genetic complexity and financial incentives for ongoing treatments hinder the development of a definitive cure.

community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

124 upvotes 2 years ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

View more "blood vessel development" in community →

Learn

7 / 18 results

learn Vascular Endothelial Growth Factor

How does Vascular Endothelial Growth Factor (VEGF) differ from DHT-blocking treatments for androgenic alopecia? VEGF promotes blood vessel growth, while DHT-blocking treatments reduce hormone effects on hair follicles.

learn Thymosin Beta 4

learn Beta Polypeptide

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Epidermal Growth Factor

learn capsicum

How does capsicum improve scalp circulation and boost growth? Capsaicin dilates blood vessels through TRPV1 activation, so capsicum is expected to raise scalp blood flow, but every human hair-loss study used it inside a multi-ingredient formula — and the strongest one gave it orally, not on the scalp — so its effect on hair by itself is unproven, and it is a known skin irritant.

learn Platelet-Rich Plasma

What is Platelet-Derived Growth Factor Beta Polypeptide, and how does it help stimulate new hair growth? PDGF-BB is a growth factor that signals to dermal papilla cells and promotes blood-vessel formation; mouse studies report it can push follicles into the growth phase, and human evidence comes only indirectly from PRP trials. No PDGF product is approved for hair restoration and there is no published human trial of PDGF-BB on its own.

View more "blood vessel development" in learn →

Clinics

3 / 3 results

Experts

— no results

Try a deeper search in experts →