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community The people this data actually matters for aren't talking about efficacy numbers

9 upvotes 4 months ago

Oral minoxidil can cause cardiovascular issues, but an extended release formulation may reduce side effects like heart rate and blood pressure spikes. This new formulation offers a safer option for those who previously had to stop due to health concerns.

community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 194 upvotes 1 year ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community New baldness drug boosts hair coverage by up to 86% in six months

719 upvotes 3 months ago

A new extended-release oral minoxidil formulation claims to improve hair growth by maintaining steady blood levels, reducing side effects like hypotension, and potentially benefiting female hair loss. However, it is not considered groundbreaking as it builds on existing minoxidil treatments, and its effectiveness compared to current doses is debated.

community Attention Guys, I highly recommend everyone to add this to your daily routine

in Microneedling 268 upvotes 1 year ago

Adding a daily scalp massage with an acupressure device before applying minoxidil can enhance its effects by improving blood circulation, with no side effects. Users are advised to continue microneedling weekly and consider using a derma stamp to avoid scarring.

community How is it possible for someone to be a non responder to ORAL minoxidil?

in Minoxidil 66 upvotes 2 years ago

Some individuals do not respond to oral minoxidil for hair loss, despite it generally working by improving blood flow to hair follicles. Factors like metabolism, drug interactions, and individual variations in the drug's activation may influence its effectiveness.

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Research

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research Hypertension: sex-related differences in drug treatment, prevalence and blood pressure control in primary care

4 citations , January 2023 in “Journal of Human Hypertension”

This review discusses sex-related differences in antihypertensive treatment and reports original data showing better blood pressure control in women than men until their late sixties, when the trend reverses.

research Repurposing existing drugs for COVID-19: an endocrinology perspective

34 citations , September 2020 in “BMC Endocrine Disorders”

This review highlights that while dexamethasone may reduce mortality in severe COVID-19, no other drugs have proven effectiveness for treatment, emphasizing the need for clinical trials of existing medications.

research COVID-19 and hypopituitarism

15 citations , August 2021 in “Reviews in endocrine and metabolic disorders”

This review discusses hypopituitarism's bidirectional relationship with COVID-19 due to metabolic comorbidities and pituitary risks, but it reports no new clinical results.

research Acne keloidalis nuchae: risk factors and associated disorders – a retrospective study

27 citations , June 2017 in “International Journal of Dermatology”

This study found that acne keloidalis nuchae was associated with pseudofolliculitis barbae, chronic scalp folliculitis, and aspects of the metabolic syndrome, particularly hypertension, in the examined population.

The 46th Annual Meeting of the Irish Endocrine Society Programme and Abstracts 2022

research The 46th Annual Meeting of the Irish Endocrine Society Meeting Programme and Abstracts 2022

October 2024 in “Irish Journal of Medical Science (1971 -)”

In this study, TENS of the T6 dermatome over a longer term was explored for its effects on weight, blood pressure, heart rate, and appetite-regulating hormones in obese subjects with moderate obstructive sleep apnea; however, results are not reported in the abstract.

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learn Hair Transplant

Can a diabetic patient undergo a hair transplant? Diabetic patients can have hair transplants if their condition is well-controlled.

learn Minoxidil

From hypertension to hair: the unexpected story of minoxidil Minoxidil was developed as an oral blood-pressure drug and approved as Loniten in 1979; unwanted hair growth in patients led to topical Rogaine, approved for men in 1988 and for women in 1991. Trials support topical minoxidil for pattern hair loss, while low-dose oral minoxidil is a prescription drug used off-label and needs medical supervision.
What are the side effects of minoxidil, and can oral minoxidil affect your heart? Minoxidil can cause side effects, and because it was designed as a blood-pressure drug, some of them involve the heart and circulation. Published studies of low-dose oral minoxidil describe mostly mild problems, but fluid around the heart, pericarditis and other serious events have been reported, and the long-term picture is still being studied. Do not start, stop or change minoxidil without a doctor, and if you develop chest pain, a racing heartbeat, shortness of breath, fainting, swelling or rapid weight gain while using it, stop and seek medical care.

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