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Research

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research Study of thin films and nanoparticles obtained by self-assembly of block copolymers and their interactions with an oligo / polysaccharide

April 2011

This study observed that chitosan-decorated PS404-b-PAA63 nanoparticles may enhance skin retention and reduce permeation flux of finasteride, suggesting potential for improved transdermal delivery.

research Etude de films minces et de nanoparticules obtenus par auto-assemblage de copolymères à blocs et leurs interactions avec un oligo/polysaccharide

April 2011 in “HAL (Le Centre pour la Communication Scientifique Directe)”

This study suggests that polymersomes decorated with chitosan improve the transdermal delivery of finasteride, providing an alternative drug delivery system with higher drug retention in the skin.

research Transdermal delivery of mixnoxidil with block copolymer nanoparticles

181 citations , July 2004 in “Journal of controlled release”

In this study, researchers found that in hairy guinea pig skin, minoxidil delivered via 40-nm nanoparticles had higher skin penetration than 130-nm nanoparticles, indicating nanoparticle size affects permeation.

research Transdermal delivery of mixnoxidil with block copolymer nanoparticles

253 citations , June 2004 in “Journal of Controlled Release”

The research observed that 40-nm self-assembled nanoparticles enhanced minoxidil penetration in hairy guinea pig skin compared to 130-nm nanoparticles, but this size effect was absent in hairless skin.

research Novel micelle formulations to increase cutaneous bioavailability of azole antifungals

109 citations , March 2011 in “Journal of controlled release”

This study found that econazole nitrate delivered via MPEG-dihexPLA micelles significantly increased skin deposition compared to Pevaryl® cream, potentially enhancing drug bioavailability and clinical efficacy.

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Learn

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learn Black Castor Oil

learn Black Cohosh

learn Black Cumin

learn Black Kumin

learn Black pepper

learn procapil

Does Procapil block DHT without affecting hormones? What the evidence shows Procapil's supplier describes it as inhibiting 5-alpha reductase at the scalp without changing hormone levels, but the published support is cell and animal work plus one small human study of a caffeine-plus-Procapil formula. It is a cosmetic ingredient, not an approved hair-loss treatment, and no trial has compared it with finasteride or minoxidil.

learn Baicapil

Does Baicapil block DHT? What the evidence shows No published study shows that Baicapil blocks DHT — the only data on the ingredient itself is the manufacturer's own unpublished dossier, and the baicalin research behind the claim is cancer cell-line work in which the effect was explicitly independent of the androgen receptor.

learn Pumpkin seed oil

Does pumpkin seed oil block DHT, the hormone linked to male and female pattern baldness? Pumpkin seed oil has not been shown to lower DHT in people. One small, supplier-funded trial of a branded supplement reported more hair after 24 weeks but did not measure DHT (Cho et al. 2014).

learn Hydrocortisone

Is hydrocortisone effective for stopping inflammation that blocks hair growth? Sources describe hydrocortisone as a short-course treatment for scalp inflammation such as seborrhoeic dermatitis or eczema, and no verified trial tests it as a hair-regrowth treatment; the corticosteroids used for alopecia areata are the potent prescription ones, and prolonged use of any topical steroid on the scalp risks skin thinning.

learn Exosomes

What does Fluridil do on the scalp, and how does it block the DHT hormone? Fluridil is a topical anti-androgen sold in some European countries. One small 2002 trial led by its developer reported more hairs in the growth phase; it is not FDA-approved and the evidence is limited.

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Community Join

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community Black light diagnosis of folliculitis

3 upvotes 2 months ago

A user observed orange fluorescence on their nose and hair under a black light, indicating Cutibacterium acnes, which may contribute to hair loss alongside androgenic alopecia. A suggestion was made to use coal tar shampoo to address the issue.

community People that don’t have 4c hair which is mostly all races that aren’t black have it better than us. Yall can have a receding hairline like this and still pull it off but I end up looking like this with mine, even when I grow my hair out 😭

502 upvotes 8 months ago

Black individuals may embrace baldness better due to less contrast between hair and skin. Finasteride is suggested for hair loss management, and natural styles like buzz cuts are recommended.

community Black market pp405? Title title

in Treatment 8 upvotes 8 months ago

PP405 is likely fake, and JXL069 is an unrefined prototype with unknown side effects. It's advised to wait for the official PP405 release.

community Black seed oil rosemary oil and microneedling success

4 upvotes 3 years ago

The user experienced success in reducing hair thinning using a combination of rosemary oil, black seed oil, and microneedling, avoiding finasteride and minoxidil due to side effects. They later stopped using black seed oil due to concerns about increased testosterone.

community Black Cumin Seed Oil

1 upvotes 5 years ago

Black cumin seed oil may stimulate hair regrowth due to thymoquinone. It can be consumed or applied topically.

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Clinics

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Hair Loss Treatments
Shibuya 3rd Block ClinicSetagaya · JP

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