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research Demethylation of ITGAV accelerates osteogenic differentiation in a blast-induced heterotopic ossification in vitro cell culture model

11 citations , December 2018 in “Bone”

This study found that a high-energy shock wave can increase osteogenic activities in human mesenchymal cells, offering insights into potential therapeutic targets for trauma-induced heterotopic ossification.

research Leukemia cutis of the scalp masquerading as 'Kerion' in a child

January 2023 in “Indian dermatology online journal”

In this case report, an 8-year-old boy's crusted scalp lesions and alopecia initially mimicking kerion were ultimately diagnosed as Pre-B acute lymphocytic leukemia after histopathological evaluation revealed leukemia cutis.

research Unleashing the Furry Beast: Exploring the Fascinating World of Hypertrichosis Lanuginosa

July 2023 in “International journal of physiology”

This article outlines hypertrichosis lanuginosa, emphasizing its rarity, potential congenital or acquired nature, association with malignancy, challenges in diagnosis, limited treatment options, and the need for more research to understand its mechanisms.

research Potential mechanisms of minoxidil-induced hair growth in alopecia areata

26 citations , March 1987 in “Journal of the American Academy of Dermatology”

This study suggests that topical minoxidil may aid hair regrowth in alopecia areata through synergistic effects on follicular epithelium and lymphocyte-mediated immunological responses, alongside its vasodilatory properties.

research BIPHENOTYPIC LEUKAEMIA

1 citations , November 1983 in “The Lancet”

Acute leukemias with the Philadelphia chromosome may be biphenotypic, and identifying this is important for proper treatment.

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community DHT Isn’t the Only Factor in Hair Loss and That Might Be the Key to a Real Cure

373 upvotes 6 months ago

Hair loss involves more than just DHT, with genetic factors like TRPS affecting hair follicles. Treatments such as Amplifica's AMP-601 and AMP-303 target stem cells for potential hair growth solutions.

community How ET-02 Works. Also no proof that it's better than Minoxidil. At least for now.

44 upvotes 1 year ago

ET-02, a PAI-1 inhibitor, is not proven to be more effective than Minoxidil for hair loss. Other treatments like finasteride, dutasteride, PP405, and AMP-303 are also discussed, focusing on cellular senescence and oxidative stress.

community PP405 bandwagon, time to resume the hype train.

164 upvotes 1 year ago

PP405 shows promise in hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil, with significant results in just four weeks. The treatment is still in early stages, with further trials needed to determine its long-term effectiveness and optimal dosage.

community Great news recently for people with hairloss!

in Research/Science 113 upvotes 1 year ago

A potential treatment for alopecia involving a protein that calms hair follicles has shown promise in rats, but skepticism remains about its applicability to humans. Many users express doubt about the timeline for effective hair loss treatments, comparing it to past unfulfilled promises.

community Did UCLA Just Cure Baldness? Check this Out!

in Research/Science 968 upvotes 1 year ago

UCLA's PP405 shows promise in reactivating dormant hair follicles for hair loss treatment but is still in clinical trials. Minoxidil and finasteride remain common treatments until PP405 becomes available.

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