111 citations
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August 2002 in “Journal of Medicinal Chemistry” This study reports that 2-(1-Adamantyl)-4H-thiochromen-4-on-6-O-sulfamate is the most potent steroid sulfatase inhibitor identified so far, exhibiting 170-fold higher activity than the lead compound estrone sulfamate.
April 2021 in “Annales de Dermatologie et de Vénéréologie - FMC” This review discusses biphasic alopecia, where non-scarring forms like traction alopecia and androgenetic alopecia may progress to follicle destruction, emphasizing the role of chronic inflammation and the importance of clinician-pathologist collaboration, but provides no new clinical results.
29 citations
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January 1996 in “Journal of Pharmaceutical Sciences” This study developed a theoretical model that suggests finasteride may completely inhibit 5AR type 2, but not sufficiently suppress type 1, leading to only partial reduction of dihydrotestosterone at clinical doses.
34 citations
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April 2009 in “Skin Pharmacology and Physiology” This study found that Minoxidil had biphasic effects on normal human keratinocytes, stimulating proliferation at micromolar doses, but showing antiproliferative, pro-differentiative, and cytotoxic effects at millimolar concentrations.
January 2026 in “RSC Advances” The hydrogel helps heal wounds without scars by releasing two drugs gradually.
