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      research Transport of Biotin in Human Keratinocytes

      53 citations , March 2003 in “Journal of Investigative Dermatology”
      This study found that human keratinocytes express a sodium-dependent multivitamin transporter for biotin, pantothenic acid, and lipoic acid, including a highly specific biotin transport component.
      Biotin-Responsive Alopecia and Developmental Regression

      research BIOTIN-RESPONSIVE ALOPECIA AND DEVELOPMENTAL REGRESSION

      74 citations , July 1979 in “Lancet”
      This case report describes a 10-month-old boy with dermatitis, alopecia, and hypotonia who showed dramatic improvement with oral biotin, suggesting a possible defect in biotin absorption or transport.
      Evaluation of New Pregnane Derivatives as 5α-Reductase Inhibitors

      research Evaluation of New Pregnane Derivatives as 5.ALPHA.-Reductase Inhibitor.

      23 citations , January 2001 in “Chemical & Pharmaceutical Bulletin”
      This study found that several synthesized pregnane derivatives exhibited significant inhibitory effects on testosterone conversion to dihydrotestosterone and reduced related androgenic parameters in multiple pharmacological models.

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