research BIOLOGICAL ACTIVITY OF ANTIANDROGENS
This review discusses the biology of antiandrogens and highlights available bioassay models to predict their therapeutic effects on human skin, reporting no new clinical results.
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5 / 447 resultsresearch K6/ODC transgenic mice as a sensitive model for carcinogen identification
This study found that the K6/ODC transgenic mouse model is highly sensitive to identifying genotoxic carcinogens, showing 100% concordance with traditional rodent bioassays.
research A COMPARTMENTAL MODEL OF URANIUM IN HUMAN HAIR FOR PROTRACTED INGESTION OF NATURAL URANIUM IN DRINKING WATER
This study developed a model predicting uranium excretion in human hair from drinking water exposure, suggesting it is a viable indicator for assessing internal uranium burden.
research 778 Designing and utilizing a c-Rel specific bioassay in drug repurposing screen for HNSCC
A new test helps find drugs to treat head and neck cancer by targeting c-Rel.
research Novel and established potassium channel openers stimulate hair growth in vitromodes of action in hair follicles.: implications for their
In this study, deer hair follicles were shown to be an effective in vitro bioassay model, demonstrating that K(ATP) channel modulators directly influence hair follicle growth through specific channel types.
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