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research The Implication of Mechanistic Approaches and the Role of the Microbiome in Polycystic Ovary Syndrome: A Review

1 citations , January 2023 in “Metabolites”

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.

research Alopecia After Injection of ATX-101 for Reduction of Submental Fat

31 citations , May 2017 in “JAAD Case Reports”

ATX-101 injections can cause hair loss.

research Generalized Pruritus in Primary Sclerosing Cholangitis: Implications of Histamine Release by Lysophosphatidic Acid

5 citations , June 2015 in “British Journal of Dermatology”

A certain medication improved severe itching in a boy with liver and bowel disease by reducing histamine levels, suggesting a new treatment target.

research Effects of Wet Cupping on Blood Components, Especially Skin-Related Parameters of Healthy Cases: A Case Control Metabonomic Study

2 citations , June 2016 in “Journal of skin and stem cell”

Wet cupping blood has different components than regular venous blood, which might affect skin disorder treatments.

research Expression, Characterization, and Structural Analysis of Human Liver Delta4-3-Ketosteroid 5beta-Reductase (AKR1D1) and Its Disease-Related Mutant P133R

January 2009 in “ScholarlyCommons (University of Pennsylvania)”

The P133R mutation in AKR1D1 enzyme causes harmful bile acid buildup, explaining related health issues.

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community Bile Acid-Mediated DHT Dysregulation Hypothesis

in Research/Science 13 upvotes 1 year ago

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

community Cell senescence-targeted treatment for hair loss, has anyone tried any products/enzymes etc. that use this theory

in Research/Science 5 upvotes 11 months ago

DHT causes hair loss by driving cells into senescence, and a polyphenol in black chokeberry may reverse this. A product using this theory is being considered for use alongside finasteride, minoxidil, and microneedling.

community 28M experiencing thinning - first timer here, please help

cgem753 in Treatments 370 upvotes 3 months ago

A 28-year-old male experiencing hair thinning is considering minoxidil and finasteride. Minoxidil helps regrow hair, while finasteride prevents further loss; both are usually lifelong treatments.

community Huberman tweet about finasteride

in Finasteride/Dutasteride 278 upvotes 2 years ago

The conversation is about the side effects of finasteride, including Post Finasteride Syndrome, with varied personal experiences and differing views on the credibility of information sources. Some participants also discuss using minoxidil as a hair loss treatment.

community Don’t know what to do, losing confidence everytime I look at the mirror

LocalEngineer in General 391 upvotes 4 months ago

A 28-year-old in Turkey is experiencing hair loss, affecting his confidence and mood. He uses various supplements and shampoos, and is considering topical finasteride/dutasteride and minoxidil for treatment.

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